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Background: Conjunctivitis is a common cause of reference to pediatrician and general hospitals. The common method of treatment is prescription of antibiotics however, there are concerns over the development of antibiotics resistance and their adverse effects. Therefore, this study was done to compare the effects of boiled water as supplementary treatment and antibiotics on the severity of infants' conjunctivitis. Materials and Methods: In this clinical trial, 110 infants referring to the Pediatric Clinic of Amir Kabir Hospital in Arak were randomly allocated to 2 groups. The first group (intervention) received boiled water together with ophthalmic erythromycin ointment 1% and sulfastamid ophthalmic solution 10% four times a day and the second group (control) just received antibiotics. Severity of infants conjunctivitis on the first, third, and seventh days of treatment were compared between the two groups using SPSS software. Results: On the 3rd day, 18.2% of the infants in the intervention group and 9.1% of the infants in the antibiotics group were cured which did not indicate a significant difference (p=0.44). On the 7th day, the recovery rate was promoted to 32.7% and 34.5% in the intervention and control groups, respectively (p>0.05). Mild severity cases were 58.2% in the intervention and 45.5% in the control groups (p>0.05) while moderate severity cases of conjunctivitis were 9.1% and 20% in the intervention and control groups, respectively (p>0.05). Conclusion: Although the number of infants who were cured was more in the boiled water group with antibiotics group and the intensity and duration of their disease were less than the control group, these differences were not statistically significant.

Keywords: Antibiotic, Boiled water, Conjunctivitis, Infants

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