Background: Human brain consists of two hemispheres with contralateral control of the body. One hemisphere's function is predominate to another, so one side of the body is more powerful in performing special tasks comparing the other which this property is almost used to determine predominant hemisphere of the brain. This analytic study performed to assess the effect of handedness and gender on the result of school readiness assessment examination in children.

Materials and Methods: Of 6 to 6.5 years old children living in middle socioeconomic regions of Qazvin city, referred to preschool Examining center to assess educational readiness and other physical examination, 400 children equally of both sexes were randomly selected in two Left-Handed (LH) and Right-Handed (RH) groups to compare the results of school readiness assessment examination. The data was statistically analysed and P-Value less than 0.05 was considered significant.

Results: The results of School Readiness Assessment Examination in LH and RH children were 38.71±2.70 and 38.15±4.04, respectively without significant difference. These results were 38.8±3.8 and 38.30±3.4 in boys and girls respectively, without significant difference. Comparing RH and LH cases in each sex group did not show any significance.

Conclusion: No significance was observed comparing the results of School Readiness Assessment Examination in LH and RH groups and between two gender groups.