Volume 1, Issue 2 (Spring 1997)                   J Arak Uni Med Sci 1997, 1(2): 27-33 | Back to browse issues page

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Pedram M. Kidney and Pregnancy. J Arak Uni Med Sci 1997; 1 (2) :27-33
URL: http://jams.arakmu.ac.ir/article-1-6518-en.html
Arak University of Medical Sciences, Arak, Iran.
Abstract:   (1231 Views)
The retention of   500-900  meq sodium and  6-8  litre water, which  is b diffused between extracellular fluid space of mother and fetues is performed  in  pregnancy  slowly. When plasma  volume  increase  by  30-50%, mean  blood  pressure  decreases  by  15% approximately. In  the second  half  of  the  pregnancy, blood   pressure  increases  slowly  and  it  returns  to  its  previous  status, in  the  period  of  term. GFR  is  increases  by  30-50% in the  twelfth  week  of  pregnancy, and  it  remains  steady  until  the  term  period .Glucosuria  and  Aminoaciduria  may  be  observed  during  the  pregnancy. In this time  ureters  are  dilated  and  it  continues  until  the  twelve  weeks  after  delivery. The cardiac  output  goes  up  in  the  primary  trimester  and  then  it  remains  fixed  until  the  term. Hypertension  is  still one  of  the  main  reason  of  morality  both  in  mother  and  infetus. The best  division  of  blood  pressure  in  the  pregnancy  has  advocated  by  American  college  of  Gynecologist, which  has  got  4 parts:
A: hypertension  which  exactly  relates  to  pregnancy ( Eclampsy , Pre-eclampsy)
B:chronic  Hypertension  with  other  causes
C:Chronic  Hypertension  which  has  been  added  by  pre _Eclampsy 
D: Pregnancy  induced  Hypertension
The other crucial problems in pregnancy is  acute  renal  failure , which  may  be  causes  by  renal  isschmia  by  the  effect  of  nephrotoxic  agent. The cellular lesion might be revercible. It  might  be  accomparied with complete  renal  function  and  might  be  irreversible, therefore  it  may  lead  to  renal  cortical necrosis. In addition to usual reasons of acute  failure , some  of  them  relates  specifically  to  pregnancy. Only  infectious, criminal  abortions  and  malignant  vomiting  are  reasons of  failure in  the  beginning  of  pregnancy, which  severe  pre-eclampsy, placenta and  placenta  abruption  are  the  main  reasons of  renal  failure  in  the  final  phase  of  pregnancy.
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Type of Study: Review Article | Subject: Obstetrics & Gynocology
Accepted: 1997/03/21

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