When chronic renal failure with chronic and progressive course produce uremic syndrome. It can be treated in two ways: dialysis or kidney transplanatation. In CRF one of the complications is hypertension which is modified after dialysis, but in some patients hypertension is resistant and the BP doesn’t decreases after dialysis and even increases after that. The reason for this, is known as reduction of intravascular load after dialysis and high level of plasma renin. So it is advised to use the ACE inhibitor drugs to minimize this complication.
1-From 80 dialysis patients, 18 ones had resistant hypertension to dialysis or elevated BP after dialysis.
2-By using 5 mg enalapril (ACE inhibitor) 0.5 hour before dialysis and systolic and diastolic blood pressure were reduced after dialysis(PV<0.01)