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Volume 4, Issue 2 (Summer 2001)                   J Arak Uni Med Sci 2001, 4(2): 22-27 | Back to browse issues page

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Sadeghi A, Rozati H, Golestani M, Moshtagh A, Sadeghi M, Sari Z. Chromosomal Study of 100 Children and Adolescenes With Mental Retardation. J Arak Uni Med Sci. 2001; 4 (2) :22-27
URL: http://jams.arakmu.ac.ir/article-1-6657-en.html
1- Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
2- Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
3- Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Abstract:   (233 Views)
About  3-5  percent  of  population  suffer  from  mental  retardation  (MR)  mildly  to  severely.  One  of  the  most  common  causes  of  Mr  is  chromosomal  aberrations.  In  this  research, Chromosmal  study  was  performed  for  100  Mental  Retarders (MRS)  by  G-banding  Method. 100  MRS  were  suffering  from  downs  syndromes: 21  cases  with  21  free  Trisomy, 1 case  chromosomal  mosaism  and  residual  case  had  Robertsonian  traslocation  14; 21  also  chromosomal  mosaism.  Other  8  MRS  had  be  structural  aberrations  in  chromosmals  such  as  inversion (3  cases), partial  trisomy (1  case), ring  22  chromosme  (1  case)  and  breakages  in  different  chromosmes  (3  cases).   The  results  showed  that  chromosomal  aberrations  are  frequent  between  Mental  Retarderes  and  the  most  common  chromosomal  aberrations  occure  between  MRS is  21  free  trisomy.
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Type of Study: Original Atricle | Subject: Pediatrics
Accepted: 2001/06/22

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