Introduction: Laryngoscopy and intratracheal intubation are one of the most painful and stimulant procedures with a severe autonomic responses. This research was performed to investigate affects of xylocaine and sufentanil on blood pressure and herat rate due to laryngoscopy and intratracheal intubation.
Materials and Methods: This research was performed on 100 patients in ASA class 1,2 which were condidated for elective surgery. Patients were divided into two equal groups. For first group xylocaine 1.5mg/kg was injected 90s before laryngoscopy and the second received 0/2 mcr/kg sufentanil 120s before that, then laryngoscopy and intratracheal intubation was performed. Maintenance of anesthesia was the same for two groups. Herat rate and blood pressure were measured from the beginning of the laryngoscopy till 9 minutes after that, with three minutes interval.
Results: Finding showed that in the time of laryngoscopy, sufentanil and xylocaine had equal affects on hemodynamic changes. Also there was no significant difference between two named drugs on diastolic pressure. But in the third, sixth and ninth minute after laryngoscopy sufentanil controlled systolic blood pressure and heart rate significantly better than xylocaine.
Conclusion: Findings of this survey showed that sufentanil could manage hemodynamic changes due to laryngoscopy and intratracheal intubation netter than xylocaine. with due attention to low side effect of sufentanil. It is suggest to use this drug for high risk patients.
Type of Study:
Original Atricle |
Subject:
Basic Sciences Received: 2021/01/27 | Accepted: 2004/06/30