Volume 7, Issue 2 (Summer 2004)                   J Arak Uni Med Sci 2004, 7(2): 28-32 | Back to browse issues page

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Talebi H, Modir H. Comparison of Effects of Xylocaine and Sufentanil on Herat Rate and Blood Pressure Due to Laryngoscopy and Intratracheal Intubation. J Arak Uni Med Sci 2004; 7 (2) :28-32
URL: http://jams.arakmu.ac.ir/article-1-6784-en.html
Abstract:   (985 Views)
Introduction: Laryngoscopy  and  intratracheal  intubation  are  one  of  the  most  painful  and  stimulant  procedures  with  a  severe  autonomic  responses.  This  research  was  performed  to  investigate  affects  of xylocaine  and  sufentanil  on  blood  pressure  and  herat  rate  due  to  laryngoscopy  and  intratracheal  intubation.
Materials  and  Methods:  This  research  was  performed  on  100  patients  in  ASA  class  1,2 which  were  condidated  for  elective  surgery.  Patients  were  divided  into  two  equal  groups. For  first  group  xylocaine  1.5mg/kg  was  injected  90s  before  laryngoscopy   and  the  second received  0/2 mcr/kg  sufentanil  120s  before  that, then  laryngoscopy  and  intratracheal  intubation  was  performed.  Maintenance  of  anesthesia  was  the  same  for  two  groups.  Herat  rate  and  blood  pressure  were  measured  from  the  beginning  of  the  laryngoscopy  till  9  minutes  after  that, with  three  minutes  interval.
Results:  Finding  showed  that  in  the  time  of  laryngoscopy, sufentanil  and xylocaine  had  equal  affects  on  hemodynamic  changes.  Also  there  was  no  significant  difference  between  two  named  drugs  on  diastolic  pressure.  But  in  the  third, sixth  and  ninth  minute  after  laryngoscopy  sufentanil  controlled  systolic  blood  pressure  and  heart  rate  significantly  better  than  xylocaine.
Conclusion: Findings of  this  survey  showed  that  sufentanil  could  manage  hemodynamic  changes  due  to  laryngoscopy  and  intratracheal  intubation  netter  than  xylocaine. with  due  attention  to  low  side  effect  of  sufentanil. It  is  suggest  to  use  this  drug  for  high  risk  patients.
 
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Type of Study: Original Atricle | Subject: Basic Sciences
Received: 2021/01/27 | Accepted: 2004/06/30

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