TY - JOUR T1 - The effect of consuming aerial part of Silybum marianum on blood glucose and lipids in diabetic rats TT - بررسی اثر مصرف بخش هوائی گیاه ماریتیغال بر میزان گلوکز و لیپیدهای خون در موش صحرایی دیابتی JF - HBI_Journals JO - HBI_Journals VL - 10 IS - 2 UR - http://jams.arakmu.ac.ir/article-1-8-en.html Y1 - 2007 SP - 31 EP - 38 KW - Silybum marianum KW - glucose KW - lipid KW - diabetes mellitus KW - rat N2 - Introduction: Use of medicinal plants for decreasing blood glucose and lipids to normal level is clinically important. In this respect, Silybum marianum (SM) is a plant that can lower lipid peroxidation and lipids in an experimental model of hyperlipidemia. Therefore, the effect of chronic oral administration of this plant on serum glucose, triglyceride, total cholesterol, and HDL and LDL cholesterol level of diabetic rats was investigated. Materials and Methods: In this experimental study, female rats (n=36) were randomly divided into 4 groups, including control, SM-treated control, diabetic, and SM-treated diabetic groups. The treatment groups received oral administration of plant-mixed pelleted food (6.25%) for 4 weeks. Serum glucose, triglyceride, total cholesterol, LDL and HDL cholesterol levels were determined before the intervention, and at 2nd and 4th weeks after the intervention. Data was analyzed using repeated measure ANOVA, One way ANOVA, student and pairt T and Tukey tests. Results: Serum glucose level in diabetic group was increased in seond and 4th weeks after the intervention as compared to one week before that (p M3 ER -