TY - JOUR T1 - The comparison betweenthe effects of hyaluronic acid vaginal suppository and vitamin E on the treatment of atrophic vaginitis in menopausal women TT - مقایسه تاثیرشیاف واژینال هیالورونیک اسید با ویتامین E در درمان آتروفی واژن در زنان یائسه JF - HBI_Journals JO - HBI_Journals VL - 15 IS - 6 UR - http://jams.arakmu.ac.ir/article-1-1326-en.html Y1 - 2012 SP - 57 EP - 64 KW - Hyaluronic acid KW - Menopause KW - Vaginal atrophy KW - Vitamin E N2 - Background: Urogenital atrophy is a common problem after menopause and quality of life in post-menopauseis seriously affected by the symptoms associated with vaginal atrophy. The aim of this study was to compare the effectiveness of the vaginal suppository of hyaluronic acid and vitamin E in atrophic vaginitis treatment. Materials and Methods: This randomized double-blind clinical trialwas carried out in Ahvaz (Iran) from August to December 2010. Forty postmenopausal women with symptoms of vaginal atrophy were randomly allocatedto two groups to take vaginal suppositories of either 5 mg hyaluronic acid sodium salt (n=20) or 1 mg vitamin E (n=20) for 8 weeks. The symptoms of vaginal atrophy were evaluated by a self-assessed 4-point scaleand the composite score was determined asnone, mild, moderate, and severe in four periods. Results: The results showed that the symptoms were relieved significantly in both groups (P M3 ER -