TY - JOUR JF - HBI_Journals JO - J Arak Uni Med Sci VL - 24 IS - 5 PY - 2021 Y1 - 2021/11/01 TI - The Potential of the Use of the Flavonoid Fisetin in the Treatment of Coronavirus by Inhibition of Angiotensin Converting Enzyme 2 TT - پتانسیل استفاده از فلاونوئید فیستین بر درمان کروناویروس از طریق مهار آنژیوتانسین 2 N2 - In December 2019, a new type of coronavirus called COVID-19 was identified as an unknown cause of pneumonia in Wuhan, China. The pandemic virus was transmitted to humans from a type of seafood that could spread significantly among humans in a short time. Clinical signs of coronaviruses include fever, severe sweating, cough, pneumonia, and a weakened immune system, with acute cases leading to death. One of the most important coronavirus receptors in the host cell is the angiotensin 2 converting enzyme. It is noteworthy that the patient’s recovery process increases during the inhibition of angiotensin 2 converter enzyme. Therefore, the administration of drugs that inhibit this enzyme can be effective in recovering a patient with coronavirus. Flavonoids are one the inhibitors of the angiotensin-converting enzyme, which is abundant in fruits and vegetables. Fistula, a type of flavonoid known in nature as an antioxidant and anti-inflammatory agent in the treatment of many, can be effective in the treatment of coronavirus by inhibiting the enzyme converter angiotensin 2. SP - 640 EP - 645 AU - Azadeh, Seyedeh Sara AU - Keshmiri Neghab, Hoda AD - Department of Biology, Faculty of Basic Sciences, Sciences and Research Branch, Islamic Azad University, Tehran, Iran. KW - Angiotensin Converting Enzyme KW - Coronavirus KW - Flavonoid KW - Fisetin UR - http://jams.arakmu.ac.ir/article-1-6362-en.html DO - 10.32598/jams.24.5.6230.1 ER -