TY - JOUR T1 - Androgenic Effect of Origanum vulgarel L.spp viride extract on Hormone Level of Pituitary - gonadal Axis in Mature Male Vistar Rats TT - اثر آندروژنیکی عصاره مرزنجوش بر میزان هورمون‎های محور هیپوفیز – گناد در موش‎های صحرایی نر بالغ از نژاد ویستار JF - HBI_Journals JO - HBI_Journals VL - 14 IS - 6 UR - http://jams.arakmu.ac.ir/article-1-794-en.html Y1 - 2012 SP - 89 EP - 96 KW - Origanum vulgare KW - Androgenic effect KW - Testosterone KW - Luteinizing stimulated hormone (LH) KW - Follicular stimulating hormone N2 - origanum vulgare l.spp viride was used in ancient medicine and it was medicated for digestive disease, diabetes, remedy of trauma. While antimicrobial, ant diabetic, anticancer and antioxidant effect of this plant was proved but there is done no study for its effect on reproductive system. Therefore the purpose of recent study is surveying eventual androgenic effect of this plant on hormonal level of pituitary - gonadal axis in mature male vistar rats. Materials and Methods: recent study was done on five groups of male rats of vistar race and every group includes nine rats. The control group received no drug. The sham group received physiological serum and experimental groups of A, B and C were received the ethanolic extract of origanum vulgare l. with concentration of 40, 20, 10 mg/kg body weight respectively with gavaj for 14 days. Then levels of FSH, LH and TSH hormones in blood sample was measured with RIA method and obtaining result was compared between control group and other groups. Data was analyzed with SPSS software and statistical method of ANOVA and Tukey test. In this research, significant level was p M3 ER -