fa تأثیر 12 هفته تمرین مقاومتی بر سطوح سرمی مایونکتین و FGF-21 در مردان میانسال غیرفعال عمومى General پژوهشي اصیل Original Atricle <span style="font-size:11pt"><span style="line-height:101%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:101%"><span b="" nazanin="" style="font-family:"><span style="color:black">مقدمه:</span></span></span></span></b><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:101%"><span b="" nazanin="" style="font-family:"><span style="color:black"> با توجه به سنتز و آزادسازی میوکین‌ها از بافت عضلانی در جریان اجرای تمرینات ورزشی و ارتباط میوکین‌ها با توسعه قدرت و افزایش حجم عضلانی، هدف از مطالعه حاضر، بررسی 12 هفته تمرین مقاومتی</span></span></span></span><span lang="FA" style="font-size:9.0pt"><span style="line-height:101%"><span b="" nazanin="" style="font-family:"><span style="color:black"> بر</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:101%"><span b="" nazanin="" style="font-family:"><span style="color:black"> سطوح سرمی مایونکتین و </span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:101%"><span new="" roman="" style="font-family:" times=""><span style="color:black">FGF-21</span></span></span></span><span style="font-size:9.0pt"><span style="line-height:101%"><span b="" nazanin="" style="font-family:"><span style="color:black"> مردان میانسال بود. </span></span></span></span><span lang="FA" style="line-height:101%"><span b="" nazanin="" style="font-family:"><span style="color:black"></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:104%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">روش کار:</span></span></span></span></b><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black"> در مطالعه‌ی نیمه‌تجربی، 40 نفر از مردان میانسال شهرستان اراک (میانگین سنی 6/02 </span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black">&plusmn;</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black"> 38/27 سال، وزن 11/23 </span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black">&plusmn;</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black"> 77/12 کیلوگرم، قد 7/22 </span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black">&plusmn;</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black"> 174/05 سانتی‌متر) انتخاب و به‌صورت تصادفی در دو گروه تمرین مقاومتی (</span></span></span></span><span lang="FA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">2</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">0 نفر) و شاهد (20 نفر) قرار گرفتند. گروه تمرینی 12 هفته تمرینات مقاومتی را به&rlm; صورت 3 جلسه در هفته و با شدت 65 تا 80 درصد قدرت بیشینه اجرا کردند. 48 ساعت قبل و پس از مداخله از تمامی آزمودنی‌ها خونگیری انجام و سطوح سرمی مایونکتین و </span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black">FGF-21</span></span></span></span><span style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black"> به روش الایزا اندازه‌گیری شد. پس از بررسی نرمال بودن داده‌ها، به ترتیب از آزمون</span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> t </span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">همبسته و</span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> t </span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">مستقل در سطح معنی</span></span></span></span><span lang="FA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">&lrm;</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:104%"><span b="" nazanin="" style="font-family:"><span style="color:black">داری کمتر از 05/0 برای تجزیه و تحلیل داده‌ها استفاده شد. </span></span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:104%"><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:102%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:102%"><span b="" nazanin="" style="font-family:"><span style="color:black">یافته‌ها:</span></span></span></span></b><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:102%"><span b="" nazanin="" style="font-family:"><span style="color:black"> تمرین مقاومتی باعث افزایش معنی‌داری در سطح سرمی مایونکتین (0/001 = </span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:102%"><span new="" roman="" style="font-family:" times=""><span style="color:black">P</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:102%"><span b="" nazanin="" style="font-family:"><span style="color:black">)، سطح سرمی </span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:102%"><span new="" roman="" style="font-family:" times=""><span style="color:black">FGF-21</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:102%"><span b="" nazanin="" style="font-family:"><span style="color:black"> (0/001 =</span></span></span></span> <span dir="LTR" style="font-size:9.0pt"><span style="line-height:102%"><span new="" roman="" style="font-family:" times=""><span style="color:black">P</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:102%"><span b="" nazanin="" style="font-family:"><span style="color:black">) و همچنین کاهش درصد چربی (0/417 = </span></span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:102%"><span new="" roman="" style="font-family:" times=""><span style="color:black">P</span></span></span></span><span lang="AR-SA" style="font-size:9.0pt"><span style="line-height:102%"><span b="" nazanin="" style="font-family:"><span style="color:black">) مردان میانسال شد.</span></span></span></span> <span dir="LTR" style="font-size:10.0pt"><span style="line-height:102%"><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></span></span></span></span></span></span><br> <b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">نتیجه گیری:</span></span></span></span></b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black"> با توجه به نتایج حاصل از این مطالعه به</span></span></span></span><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">&lrm;</span></span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">نظر می</span></span></span></span><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">&lrm;</span></span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">رسد، تمرین مقاومتی می</span></span></span></span><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">&lrm;</span></span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black">تواند با ایجاد سازگاری مثبت توسط افزایش سطوح سرمی مایونکتین و </span></span></span></span><span style="font-size:9.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><span style="color:black">FGF-21</span></span></span></span><span dir="RTL" style="font-size:9.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"><span style="color:black"> در تنظیم توده عضلانی، فرایند هیپرتروفی، فرایند رگ‌زایی و بهبود متابولیسم بدن نقش داشته باشد.</span></span></span></span> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet="">Introduction:</span></span></span></b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet=""> Considering the synthesis and release of myokines from muscle tissue during exercise and the relationship of myokines with the development of strength and increase in muscle volume, the purpose of this study is to investigate 12 weeks of resistance training on the serum levels of myonectin and FGF- There were 21 middle-aged men.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet="">Methods:</span></span></span></b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet=""> In a semi-experimental study, 40 middle-aged men of Arak city (mean age 38.27 &plusmn; 6.02 years, weight 77.12 &plusmn; 11.23 kg, height 174.05 &plusmn; 7.22 cm) were selected and randomly placed in two resistance training groups (20 people) and control (20 people). The training group performed 12 weeks of resistance training 3 times a week with an intensity of 65-80% of maximum strength. Blood was taken from all the subjects 48 hours before and after the intervention, and serum levels of myonectin and FGF-21 were checked by the ELISA method. After checking the normality of the data, they were analyzed by the correlation t-test and independent t-test at a significance level of less than 0.05.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet="">Results: </span></span></span></b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet="">Resistance training caused a significant increase in the serum level of myonectin (P = 0.001) and the serum level of FGF-21 (P = 0.001) and also decreased the percentage of fat (P = 0.417) in middle-aged men.</span></span></span></span></span></span></span></span><br> <b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet="">Conclusions:</span></span></span></b><span style="font-size:8.0pt"><span style="line-height:115%"><span ms="" style="font-family:" trebuchet=""> According to the results of this study, it seems that resistance training can have positive adaptation by increasing the serum levels of myonectin and FGF-21 in the regulation of muscle mass, hypertrophy process, angiogenesis process, and Improve the body&#39;s metabolism.</span></span></span> تمرین مقاومتی؛ هیپرتروفی عضلانی؛ فاکتور رشد فیبروبلاستی-21؛ مایونکتین Resistance training, Muscle hypertrophy, FGF-21, Myonectin 164 170 http://jams.arakmu.ac.ir/browse.php?a_code=A-10-7496-1&slc_lang=fa&sid=1 Zahra Yousefvand زهرا یوسف وند zahra13699631@gmail.com 4600319475328460088368 4600319475328460088368 No Department of Physical Education, Faculty of Literature and Human Sciences, Lorestan University, Lorestan, Iran گروه تربیت بدنی و علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه لرستان، خرم‌آباد، ایران Masoud Rahmati مسعود رحمتی Rahmati.mas@lu.ac.ir 4600319475328460088369 4600319475328460088369 Yes Department of Physical Education, Faculty of Literature and Human Sciences, Lorestan University, Lorestan, Iran گروه تربیت بدنی و علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه لرستان، خرم‌آباد، ایران Rahim Mirnasuri رحیم میرنصوری arss13871387@yahoo.com 4600319475328460088370 4600319475328460088370 No Sports Physiology, Department of Physical Education, Faculty of Literature and Human Sciences, Lorestan University, Lorestan, Iran فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه لرستان، خرم‌آباد، ایران