Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
The Need to pay Attention to Evidence-Based Medicine (EBM) in the Diagnosis and Treatment of COVID-19 Disease
580
583
FA
Nayereh
Baghcheghi
Department of Nursing, Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.
Hamid Reza
Koohestani
Department of Medical Education, Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.
Mehdi
Mesri
Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.
Mahmood
Karimi
Department of Health Education and Promotion, Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.
N/A
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Effect of Exercise on Immunological Indicators During the COVID-19 Pandemic
584
603
FA
Amir Hossein
Ahmadi Hekmatikar
Department of Physical Education, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.
Mahdieh
Molanouri Shamsi
Department of Physical Education, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.
Background and Aim: Coronavirus Disease 2019 (COVID-19), as a viral disease, has increasingly highlighted the need for lifelong exercise due to its immunological and physiological effects is necessary on health. In this review study, while examining the effects of moderate-intensity exercise on the physiological and immunological responses associated with COVID-19, appropriate exercise patterns during the COVID-19 pandemic are presented.
Methods & Materials: In this study, the search was conducted in Web of Science, Scopus, ISC, PubMed, Google Scholar, MagIran, and Noor databases on related articles using the following keywords: coronavirus, COVID-19, exercise and coronavirus, exercise and immune system, high-intensity exercise and immune system.
Ethical Considerations: All ethical principles in writing this article have been observed according to the instructions of the National Ethics Committee and the COPE regulations.
Results: Moderate-intensity exercise can help boost the function of the immune system. On the other hand, high-intensity exercise can have negative effects on the immune system, which can be a bad strategy increasing the risk of infectious diseases.
Results Moderate-intensity exercise can help boost the function of the immune system. On the other hand, high-intensity exercise can have negative effects on the immune system, which can be a bad strategy increasing the risk of infectious diseases.
Conclusion: Due to the onset of the second wave of COVID-19 in the world, it is recommended to continue to exercise at home observing the hygiene rules (maintaining humidity and disinfecting environmental surfaces) and using appropriate intensity and duration.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Extrapulmonary Manifestations of Coronavirus Disease 2019: A Narrative Review
604
613
FA
Ameneh
Omidi
Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Somayeh
Shatizadeh Malekshahi
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Parsa
Veisi
Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Background and Aim: Coronaviruses are a large family of viruses that are known to cause respiratory tract infections in humans. SARS-CoV-2 is a new type of this family initiated in late 2019 and its related disease is known as Coronavirus Disease 2019 (COVID-19). Common symptoms of COVID-19 include fever, dry cough, fatigue, myalgia, arthralgia and shortness of breath.
Methods & Materials: In This narrative review a literature search was conducted in scientific databases including Google Scholar and PubMed to find studies published from December 2019 to May 10 2020 on the role the extrapulmonary manifestations of COVID-19.
Ethical Considerations: Ethical issues (including plagiarism, misconduct, data fabrication, falsification, double publication or submission, redundancy) have been completely observed by the authors.
Results: In addition to respiratory symptoms, involvement of various organs such as gastrointestinal tract, nervous system, skin, olfactory system, cardiovascular system, liver, kidney, and eyes was also reported. Extrapulmonary manifestations of COVID-19 included anosmia, ageusia, skin rash, chickenpox-like blisters, acute cardiac failure with increased troponin levels, kidney inflammation and edema, common gastrointestinal symptoms (e.g. diarrhea, nausea and vomiting), elevated liver enzyme levels, neurological disorders (e.g. stroke), nonspecific symptoms (e.g. headache and dizziness), and decreased consciousness level.
Conclusion: The hypothetical mechanisms of various organ involvements during COVID-19 include immune-mediated inflammation such as cytokine storm, respiratory dysfunction, hypoxemia, cellular damage, or combination of these mechanisms. Further studies should be conducted on the causes of various COVID-19-induced damages to determine the exact relationship between the pathogenesis, prognosis and severity of the disease.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Molecular Structure of SARS-CoV-2 Virus and the Proposed Related Drugs
614
631
FA
Ali
Hojabr Rajeooni
Department of Virology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Parvaneh
Mehrbod
Influenza and Respiratory Viruses Department, Pasteur Institute of Iran, Tehran, Iran.
Background and Aim: Coronavirus Disease 2019 (COVID-19) is one of the most important viral diseases in the current decade which has caused widespread crisis worldwide. The disease was first reported on December 8, 2019 in Wuhan, Hubei Province, China, in the patients with acute respiratory distress syndrome. On January 8, 2020, the Centers for Disease Control and Prevention in China identified the virus, and it was named 2019-nCoV by the World Health Organization (WHO). The name of the disease was later changed to COVID-19. According to the International Committee on Taxonomy of Viruses, the virus is called SARS-CoV-2 which belongs to the family of Coronaviridae. The viruses of this family have caused outbreaks in several countries (SARS in 2003 and MERS in 2013) which have led to death and economic loss.
Methods & Materials: In this review study, COVID-19 was studied from various aspects including evolutionary process and molecular biology of its virus. The selected articles were examined based on the information available in the WHO database. SARS-CoV-2 proteins were identified molecularly and functionally using data analysis and bioinformatics methods, and then related drugs and their effects on virus replication and inhibition were investigated.
Ethical Considerations: All ethical principles were observed in this study.
Results: Studies on the structure of SARS-CoV-2 and drug therapies to inhibit the disease progression showed that the use of different pharmaceutical strategies is effective in treating COVID-19 depending on the progression of the disease. Molecular studies showed that the use of nucleoside analogues and protease inhibitors is effective in the course of the disease and intravenous immunoglobulin, aminoquinoline compounds, TMPRSS2 inhibitors and viral S protein can be effective in the early stages of disease.
Conclusion: In order to control COVID-19, it is very important to study the structure of SARS-CoV-2 virus and its biology in the body. It is essential to identify the drugs that affect the virus based on its biological structure. Due to the structural changes of the virus and successive mutations in the virus genome as well as the emergence of resistant strains or highly contagious strains, further studies on the structure of SARS-CoV-2 and its changes in the body are recommended for designing pharmaceutical and therapeutic strategies. These strategies varies according to the stage of the disease, such that some drugs prevent the virus from entering the target cells in the early stages of the disease and other drugs, in combination with the virus’ surface glycoproteins, prevent the virus antigen from binding to receptors in the host cells. In the late stages of the disease, antiviral drugs including protease inhibitors and nucleoside analogues, interfere with the replication and structure of the virus. Due to intermittent changes in the virus and the development of drug-resistant viruses, it is important to continuously review virological and clinical studies and the performance of existing drugs against SARS-CoV-2.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
A Guide to Physical Activity at Home During the Coronavirus Disease 2019 Pandemic
632
645
FA
Mohammad
Parastesh
Department of Sport Physiology and Injuries, Faculty of Sport Sciences, Arak University, Arak, Iran.
Jalil
Moradi
Department of Motor Behavior and Sport Psychology, Faculty of Sport Sciences, Arak University, Arak, Iran.
Background and Aim: Coronavirus Disease 2019 (COVID-19) pandemic has reduced the physical activity of people worldwide. The purpose of this study is to provide a practical guide for performing physical activities at home during the COVID-19 pandemic.
Methods & Materials: The study was conducted by using library method and reviewing the books and articles on home-based physical activity, to provide a scientific basis for performing physical activity at home. In this regard, various physical activities with and without equipment at homes were examined.
Ethical Considerations: This article is a review article with no human or animal sample.
Results: Home-based practical suggestions for staying active and cope with its physical and psychological consequences of the COVID-19 pandemic were reported walking or running on a treadmill, the use of stationary bikes, and body weight resistance exercise, in addition to aerobic exercise.
Conclusion: This proposed physical activity programs can be used during the pandemic at home by people with sedentary lifestyle.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
COVID-19 and Breastfeeding
646
653
FA
Zhilla
Heydarpoor
Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Leila
Valizadeh
Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Background and Aim: In the current Coronavirus Disease 2019 (COVID-19) pandemic, there have been many concerns about the transmission of the virus from the mother to the infant. This is more important due to the need for the management of breastfeeding. This study aims to review the latest studies on breastfeeding during the COVID-19 pandemic.
Methods & Materials: This is a review study on articles about breastfeeding during the COVID-19 pandemic published from December 2019 to May 2020. The search was conducted in SID, PubMed, Scopus, Science Direct, Google Scholar, Ovid, and MagIran databases using the keywords:New coronavirus, COVID-19, breast milk, and breastfeeding
Ethical Considerations: All ethical principles in writing this article have been observed according to the instructions of the National Ethics Committee and the COPE regulations.
Results: So far, there is no evidence of COVID-19 virus in breast milk or its transmission through breastfeeding. All mothers with confirmed or suspected COVID-19 should continue to breastfeed their infants in accordance with the hygiene and respiratory precautions.
Conclusion: Breastfeeding protects the baby against infectious diseases. Given that the studies reported the absence of COVID-19 virus in breast milk are very limited, this study can help mothers manage breastfeeding during the COVID-19 pandemic. Since there are still many unknowns of this emerging disease, more studies are needed on managing breastfeeding in this pandemic.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Epidemiology, Transmission Methods, Clinical Manifestations, Radiological Symptoms, Prognosis and Treatment of COVID-19 in Children
654
665
FA
Mozhgan
Hashemieh
Department of Pediatric Hematology and Oncology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background and Aim: In December 2019, the new coronavirus disease (COVID-19) was first identified in Wuhan, China, and then spread rapidly around the world, such that the World Health Organization reported it as a pandemic. This study aims to review the epidemiological findings, transmission methods, clinical manifestations, radiological symptoms, prognosis and treatment of COVID-19 in children, as well as the differences caused by the virus between children and adults.
Methods & Materials: The search was conducted in databases such as PubMod, Scopus, ScienceDirect and Google Scholar using the keywords “COVID-19”, “Coronavirus”, “Children”, and “Pandemic”.
Ethical Considerations: Ethical principles have been observed in accordance with the guidelines of the National Ethics Committee and the COPE regulations.
Results: Most of the data related to COVID-19 are related to the course of this disease in adults and related information for children is limited. Most findings suggested that the course of the disease is milder in children and the infection caused by the virus has a better prognosis in children. Due to the mild clinical symptoms in children, many of them are not diagnosed in the early stages of the infection. With the increase in the number of cases worldwide, the prevalence of this disease in children is certainly increasing.
Conclusion: COVID-19 has milder clinical symptoms and a better prognosis in children. Today, no vaccine or antiviral drug has been developed for this disease; hence, prevention is the best solution.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
SARS-COV-2: History, Genetics, and Treatment
666
685
FA
Niloofar
Agharezaee
Department of Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Flora
Forouzesh
Department of Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Background and Aim: Coronaviruses are a large family of viruses that cause disease in humans and animals. Coronavirus Disease 2019 (COVID-19) is an acute respiratory infectious disease caused by a new coronavirus. The World Health Organization has declared this infectious disease as a global pandemic.
Objective: This study aims to review the latest research advances in genetics, pathogenicity, and clinical features of COVID-19, as well as current therapies to combat this disease.
Methods & Materials: This is a systematic review study on articles published from 2010 to 2020 by searching in reputable databases such as PubMed, Scopus, Google Scholar, Web of Science, and ScienceDirect.
Ethical Considerations: Ethical principles have been observed in accordance with the guidelines of the National Ethics Committee and the COPE regulations.
Results: Examining the genome and genetic studies of the virus, it can be said that there are many similarities between different coronavirus types, but there are differences in their genomic and phenotypic structures that can affect their pathogenesis. Re-use of existing therapeutic drugs, previously designed for other infections and viral pathologies is currently the only practical approach to fight COVID-19. The tests for SARS-CoV-2 genome-specific vaccines and the therapeutic antibodies are currently being tested, but they require a long-term process and complete safety testing.
Conclusion: Rapid diagnosis of SARS-CoV-2 infection is the basis of disease control. There is currently no specific antiviral drug approved for SARS-CoV-2 infection. Therefore, preventive measures are necessary to stop and control the spread of COVID-19, according to genetic studies and the obtaining knowledge of the molecular mechanism of this virus.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Abortion Laws and Regulations in Iran and European Countries During the COVID-19 Pandemic
686
697
FA
Roya
Rashidpouraie
Department of Medical Ethics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Nader
Sharifi
Department of Medical Ethics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mina
Rashidpouraei
Department of Ultrasound, The Burwin Institute of Diagnostic Medical Ultrasound, Toronto, Canada.
Background and Aim: Abortion has always posed challenges in the areas of ethics, law, religion, philosophy, and reproductive health. Some countries have had different approaches to abortion at different times. Today, abortion is a major challenge in Iran. Social developments and increasing level of health literacy, awareness and participation of women in social and economic fields have led to incompatibility of theoretical and practical aspects in these areas. Women sometimes have abortions without attention to the national law. In Iran, the reasons for legal abortion are the life-threatening conditions of the mother and the fetus. During the Coronavirus Disease 2019 (COVID-19) pandemic, some countries have revised their abortion laws and regulations. In some countries, such as France and Finland, these revisions are permanent; in countries such Portugal and Norway, the changes are temporary; and in other countries such as Germany and Belgium, it is unclear whether the changes are permanent or temporary. In this study, we aim to review the abortion laws and regulations in Europe and Iran. Then, by discussing the new guidelines for the COVID-19 pandemic, we evaluate the effects and consequences of this pandemic on abortion.
Methods & Materials: The search was conducted in PubMed/MEDLINE, ScienceDirect, Scopus and Google Scholar as well as national databases such as SID, MagIran, and IranMedex on studies published from 2002 to 2020 using the following keywords:Abortion, illegal abortion, induced abortion, and COVID-19. Due to the onset of SARS-COV1 epidemic in 2002, all articles published between these two outbreaks were searched.
Ethical Considerations: All ethical principles were observed in this article.
Results: During the COVID-19 pandemic, some European countries revised the abortion laws and regulations, mostly due to realize the reproductive health right. It seems that, this revision has not yet been taken place in Iran.
Conclusion: With the emergence of COVID-19, some countries had revised their abortion laws and regulations to reduce unsafe abortions. It seems that during the Covid19 pandemic, due to changes in lifestyle such as social distancing and economic and social lockdowns, it needs to revise medical laws and regulations in health-oriented and time-dependent areas (such as abortion) so that the principles of medical ethics such as beneficence and maleficent, can be applied. Having COVID-19 and consequently abortion during the pandemic is one of the most challenging issues that should be addressed in terms of ethical, jurisprudential and legal aspects. Development of regulations based on ethical principles during the COVID-19 pandemic is necessary to prevent illegal and unsafe abortions.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Effect of Health-promoting Lifestyle and Psychological Well-being on Anxiety Induced by Coronavirus Disease 2019 in Non-medical Students
698
709
FA
Ayatollah
Fathi
Institute of Law Enforcement and Social Studies, Tehran, Iran.
Solmaz
Sadeghi
Department of Psychology, Institute of Charkh Niloofari, Tabriz, Iran.
Ali Akbar
Maleki Rad
Department of Biology, Faculty of Scince, Payam-e-Nour University, Tehran, Iran.
Hossein
Rostami
Department of Psychology, Institute of Charkh Niloofari, Tabriz, Iran.
Karim
Abdolmohammadi
Department of Psychology, Faculty of Psychology and Educational Sciences, Payam-e-Nour University, Tehran, Iran.
Background and Aim: Anxiety is one of the clinical signs of viral diseases such as Coronavirus Disease 2019 (COVID-19), which can threaten the immune system. This study aims to investigate the effect of health-promoting lifestyle and psychological well-being on COVID-19-induced anxiety in non-medical students
Methods & Materials: This is an analytical/correlational study conducted on 307 non-medical students of Islamic Azad University in Tabriz, Iran, who were participated voluntarily in the study. They completed the Corona Disease Anxiety Scale developed by Alipour et al. (2019), Ryff’s Scales of Psychological Well-Being (SPWB), and Health-Promoting Lifestyle Profile (HPLP) developed by Walker et al. (1987). The collected data were analyzed in SPSS v. 20 software by using the stepwise regression analysis
Ethical Considerations: This research conducted based on the Ethical Committee of University of Tabriz (TABRIZU.REC.1399.018).
Results: Two SPWB components of “personal growth” and “positive relations with others” were able to predict the COVID-19-induced anxiety, which together explained 72% of anxiety variance in students. Moreover, two HPLP components of “spiritual growth” and “responsibility” could predict the COVID-19-induced anxiety and together explained 9% of the anxiety variance.
Conclusion: Promoting personal and spiritual growth, having positive relations with others, and responsibility can significantly reduce the anxiety induced by the COVID-19.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
A Comparative Study on Anxiety of Medical and Non-medical Staff due to Exposure and Non-exposure to the Novel Coronavirus Disease
710
723
FA
Mohammad
Rahmanian
Critical Care and Pain Management Research Center, Jahrom University of Medical Sciences, Jahrom, Iran.
Ali Reza
Kamali
Department of Anesthesiology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Hadi
Mosalanezhad
Department of Health, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
Mahdi
Foroughian
Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Navid
Kalani
Center for Health and the Social Sciences, Jahrom University of Medical Sciences, Jahrom, Iran.
Naser
Hatami
Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran.
Mohammad
Heidarnezhad
Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran.
Esmaeal
Rayatdoost
Department of Emergency Medicine, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
Samaneh
Abiri
Department of Emergency Medicine, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
Background and Aim: The recent Coronavirus Disease 2019 (COVID-19) outbreak has caused a lot of stress and anxiety in the world. Given that health care workers are at the forefront of fighting against COVID-19, they are the first to be exposed to this disease.
Methods & Materials: This is a descriptive cross-sectional study conducted on 402 medical and administrative staff working in hospitals and health centers affiliated to Jahrom University of Medical Sciences in 2020. Data collection tools were a demographic form and the Corona Disease Anxiety Scale (CDAS).
Ethical Considerations: This study was approved by the Vice-Chancellor for Research of Jahrom University of Medical Sciences (Code: IR.JUMS.REC.1399.046).
Results: The mean score of psychological symptoms of anxiety in the medical staff (46.91) was higher than in the administrative staff (42.63). Its physical symptoms were also higher in the clinical staff (12.80) compared to the administrative staff (10.94). There was a significant difference between the clinical and administrative staff in terms of anxiety (P=0.030).
Conclusion: Medical staff has higher psychological and physical symptoms of anxiety compared to the non-medical staff during the COVID-19 outbreak. Therefore, in order to reduce the anxiety of medical staff, health policymakers should take the necessary measures to take care of this group.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Depression, Anxiety and Suicidal ideation of Nurses in the Outbreak of COVID-19: The Role of Demographic Variables
724
739
FA
Said
Ariapooran
Depatrment of Psychology, Faculty of Literature and Humanistic, Malayer University, Malayer, Iran.
Marzieh
Amirimanesh
Depatrment of Psychology, Faculty of Literature and Humanistic, Malayer University, Malayer, Iran.
Background and Aim: Nurses experience many psychological problems during the Coronavirus Disease 2019 (COVID-19) outbreak. This study aims to investigate the prevalence of depression, anxiety and suicidal ideation in nurses during the COVID-19 outbreak, and compare these problems in nurses based on gender, educational level, marital status and department.
Methods & Materials: This is a descriptive study conducted on 312 nurses working in hospitals in Malayer, Iran. who were selected using census method. They completed the Beck Depression Inventory, Beck Anxiety Inventory, and Scale for Suicidal Ideation questionnaire. Descriptive statistics and Multivariate Analysis of Covariance (MANCOVA) were used to analyze the collected data in SPSS v. 24 software.
Ethical Considerations: This study was approved by the Research Ethics Committee of Malayer University (Code: IR.MALAYERU.REC.1399.002).
Results: It was reported that 15.38% of nurses had moderate-to-severe depression; 46.47% had moderate-to-severe anxiety, 27.56% had plans for suicide, and 9.94% had active suicidal desire. The results of MANCOVA showed that depression (P=0.009) and anxiety (P=0.001) in female nurses was significantly higher than in male nurses. Depression and suicidal ideation of nurses with bachelor’s degree were higher compared to nurses with master’s degree (P=0.01). Anxiety and suicidal ideation of single nurses were higher compared to married nurses (P=0.01). Nurses in the emergency department (P=0.03), ICU/CCU (P=0.04) were more anxious than the pre-hospital emergency nurses.
Conclusion: Prevalence of depression, anxiety and suicidal ideation in nurses during the outbreak of COVID-19 in Iran is high. Therefore, it is recommended to use psychological therapies to reduce their depression, anxiety and suicidal ideation during the outbreak.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Prevalence, Clinical Manifestation and Mortality Rate in COVID-19 Patients With Underlying Diseases
740
749
FA
Mehrdad
Nasrollahzadeh Sabet
Department of Genetics and New Technologies, School of Medicine, Aja University of Medical Science, Tehran, Iran.
Mohammad
Khanalipour
Department of Genetics and New Technologies, School of Medicine, Aja University of Medical Science, Tehran, Iran.
Milad
Gholami
Department of Biochemistry and Genetics, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Abdolazim
Sarli
Medical Genetics Lab, Beski Hospital, Gonbad-e Kavus, Golestan, Iran.
Arefeh
Rahimi Khorrami
Department of Infectious Diseases, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Emran
Esmaeilzadeh
Department of Genetics and New Technologies, School of Medicine, Aja University of Medical Science, Tehran, Iran.
Background and Aim: The new Coronavirus Disease 2019 (COVID-19) outbreak initiated from China in late December 2019, has posed a great global health threat. Since patients with high blood pressure, diabetes, and cardiovascular diseases are at high risk of COVID-19, this study aims to investigate the prevalence, severity, clinical manifestations, and mortality rate in COVID-19 patients with underlying diseases compared to those without underlying diseases.
Methods & Materials: This study was performed on 1408 patients with COVID-19 admitted to Golestan, Hajar, Khanevadeh and Besat hospitals in Tehran, Iran. Required data including disease prevalence, severity, clinical manifestations and mortality rate in patients with and without underlying diseases were collected and then analyzed using statistical tests in SPSS software, considering a significance level of P<0.05.
Ethical Considerations: This study was approved by the AJA University of Medical Sciences (Code: IR.AJAUMS.REC.1399.091). Ethical principles have been observed in accordance with the guidelines of the National Ethics Committee and the COPE regulations.
Results: Patients were 912 men (64.8%) and 496 women (35.2%) aged 18-98 years (Mean age= 57.8 years). Results reported that 27% of patients were intubated and 21.9% were died. Blood oxygen level in 53.7% of patients was less than 93 mg/dL; 36.1% had a history of hypertension, 24.1% had a history of diabetes, and 21.7% had a history of cardiovascular disease.
Conclusion: The severity, clinical manifestations, and mortality rate of COVID-19 patients with cardiovascular disease, diabetes and hypertension are significantly different compared to those without underlying diseases.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Knowledge, Attitude and Practice of Medical and Administrative Staff in Exposure and Non-exposure to Covid 19 Virus in Jahrom: A Cross-sectional Descriptive Study in 2020
750
765
FA
Mohammad
Rahmanian
Critical Care and Pain Management Research Center, School of Medical, Jahrom University of Medical Sciences, Jahrom, Iran.
Ali Reza
Kamali
Department of Anesthesiology, Arak University of Medical Sciences, Arak, Iran.
Mahdi
Foroughian
Department of Emergency Medicine, School of Medicine, Mashhad University of Medical sciences, Mashhad, Iran.
Navid
Kalani
Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran.
Nafiseh
Esmaealpour
Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran.
Naser
Hatami
Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran.
Esmaeal
Rayat Dost
Department of Emergency Medicine, School of Medical, Jahrom University of Medical sciences, Jahrom, Iran.
Background and Aim: The COVID-19 pandemic is capable of severely affecting the mental health of health care workers, who are at the forefront of this crisis; while the official staff of health organizations is facing the same danger. Therefore, monitoring awareness and other mental health issues to understand the mediating factors and awareness of appropriate interventions is a necessary priority. Therefore, the purpose of this study was to compare the level of knowledge, attitude, and practice of medical and administrative staff in facing the COVID-19 virus.
Methods & Materials: This cross-sectional descriptive study was performed on 160 medical and administrative staff of Jahrom hospitals in 2020. Demographic information questionnaire and researcher-made questionnaire of knowledge, attitude and practice of medical personnel about coronavirus (Covid 19) were used to collect information. Data were analyzed using SPSS software version 21 and descriptive and inferential statistical tests.
Results: 65% of subjects were women and the rest were men. In most of the answers given to each item in both groups, the medical and administrative staff’s answers were close to each other. In the case of the statement "I am more likely to get a corona", 54.4% of the medical staff chose the strongly agreed option, while this percentage is 16.5% for the administrative staff. This indicates that the medical staff is very afraid of getting COVID-19. According to the results, the mean knowledge scores of the medical staff (with an average of 94.35) were significantly higher than the administrative staff (with an average of 87.75) (t=5.96, p<0.001). But the performance of administrative staff (with an average of 93.14) is significantly higher than medical staff (with an average of 87.17) (t=-2.710, p=0.007). No significant difference was observed between the mean scores of the attitude scores of both groups (p=0.438).
Conclusion: The results of this study showed that the level of awareness in the face of corona virus in the administrative staff is significantly lower than the medical staff, but the administrative staff has a better performance in facing of the corona virus than the medical staff. It seems that educational measures are necessary to increase the awareness of these people.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Evaluation of the Conformity Between Chest CT Scan Results With Molecular Diagnosis Test in Patients With COVID-19
766
773
FA
Mehrdad
Nasrollahzadeh Sabet
Department of Genetics and Biotechnology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Mohammad Foad
Heidari
DNA Molecular Identification Center, Aja University of Medical Sciences, Tehran, Iran.
Mohammad
Khanalipour
DNA Molecular Identification Center, Aja University of Medical Sciences, Tehran, Iran.
Saadat Allah
Ghaffari
Department of Genetics and Biotechnology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Milad
Jafari Ashiani
Department of Genetics and Biotechnology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Sajjad
Biglari
Department of Genetics and Biotechnology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Emran
Esmaeilzadeh
Department of Genetics and Biotechnology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Background and Aim: Since late 2019, with the emergence of a new type of coronavirus that causes a new respiratory disease called COVID-19, there have been many concerns about the spread of this disease and how to deal with it. Due to the ability of the virus to be transmitted rapidly, diagnosing the infected individuals in the early stages for isolating them is critical. This study aims to evaluate the reliability of Computed Tomography (CT) scan in diagnosing COVID-19.
Methods & Materials: Participants were 212 patients admitted to hospital with confirmed diagnosis of COVID-19. Demographic information, medical history, symptoms, and the chest CT scan results were collected and analyzed. Finally, the power of CT scans in the diagnosis of this disease was compared with the Real-Time Polymerase Chain Reaction (RT-PCR) molecular test.
Ethical Considerations: This study received ethical approval from the ethics committee of AJA University of Medical Sciences (Code: IR.AJAUMS.REC.1399.091).
Results: The sensitivity of CT scan in the diagnosis of COVID-19 was relatively high, but its false-positive results were also high.
Conclusion: CT scan is a relatively sensitive method for diagnosing COVID-19, but caution should be made due to its high false-positive results which can lead to increased financial burden on the health system.
Arak University of Medical Sciences
Journal of Arak University of Medical Sciences
1735-5338
23
5
2020
11
1
Status of Food Security in Kerman, Iran During the COVID-19 Pandemic
774
785
FA
Sajjad
Tezerji
Kerman Health Center, Kerman University Of Medical Science, Kerman, Iran.
Fatemeh
Nazari Robati
Kerman Health Center, Kerman University Of Medical Science, Kerman, Iran.
Background and Aim: Food security at individual, family, national, regional and global levels can be achieved when all people at all times have physical and economic access to adequate and healthy food to meet their nutritional needs and priorities for a healthy and active life. This study aims to investigate the status of food security and its related socioeconomic factors in households during the Coronavirus Disease 2019 (COVID-9) pandemic in Kerman, Iran.
Methods & Materials: This descriptive cross-sectional study was conducted on 500 households selected randomly from five comprehensive health centers in five districts of Kerman city in Iran. A demographic/socioeconomic questionnaires and the Persian version of the 18-item USDA Household Food Security Survey (HFSS) were used for collecting data.
Ethical Considerations: All ethical principles are considered in this article. The participants were informed about the purpose of the research and its implementation stages. They were also assured about the confidentiality of their information and were free to leave the study whenever they wished, and if desired, the research results would be available to them.
Results: There was a significant relationship between the socioeconomic factors (household size, house size, and number of amenities) and the food security. There correlation between the household size and food security was positive (R= 0.142, P<0.001), while the correlation of house size (R= -0.093, P<0.005) and number of amenities (R= -0.73, P<0.001) with food security was negative.
Conclusion: By increasing the awareness of people and improving their economic situation, it is possible to improve the food security situation of households in Kerman city.