Volume 15, Issue 2 (June-July 2012)                   J Arak Uni Med Sci 2012, 15(2): 48-53 | Back to browse issues page

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Hosseini-valami S M, Hossenini-jahromi S, Rahimibashar F. The comparison between the effects of propofol and sodium thiopental on post-extubation laryngospasm in patients undergoing tonsillectomy. J Arak Uni Med Sci. 2012; 15 (2) :48-53
URL: http://jams.arakmu.ac.ir/article-1-1027-en.html
1- qazvin university of medical science , parspaya872008@yahoo.com
2- qazvin university of medical science, 0281-3335800sahid rajaei hospital-padegan street-qazvin
3- hamedan university of medical science, 0811-2640021-51-besat hospital-shahit motahari BLV-hamedan
Abstract:   (8638 Views)
Background: One of the most important complications of tonsillectomy is laryngospasm which leads to airway obstruction, arterial hypoxemia, and hypercarbia. Thus the present study was carried out to compare the effect of propofol with sodium thiopental, as an induction agent of anesthesia, on the incidence and intensity of laryngospasm after extubation in tonsillectomy. Materials and Methods: This double-blind clinical trial was done on 60 3-12-year-old patients who were chosen for elective tonsillectomy at Qods Hospital in Qazvin. The patients were randomly divided into two equal groups. Method of anesthesia was the same in these two groups except for the induction of anesthesia one group received sodium thiopental and the other group received propofol. At the end of the operation, patients were extubated after the restoration of spontaneous respiration with adequate tidal volume and respiratory rate. Then the incidence and intensity of laryngospasm was evaluated. Data were analyzed by t-test, Chi-square, and Fisher's exact test using SPSS software. Results: Overall, 83% of the patients in the sodium thiopental group and 93% of the patients in the propofol group did not develop laryngospasm and there were no statistical differences between the two groups in terms of the incidence and intensity of laryngospasm after extubation in tonsillectomy (P=0.535). Conclusion: As an induction agent in general anesthesia, propofol has the same effect as sodium thiopental on the incidence and intensity of laryngospasm after tonsillectomy.
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Subject: Anesthesia
Received: 2011/01/28 | Accepted: 2011/07/13
* Corresponding Author Address: 2081-3335800sahid rajaei hospital-padegan street-qazvin

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