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Volume 17, Issue 1 (4-2014)                   J Arak Uni Med Sci 2014, 17(1): 0-0 | Back to browse issues page

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Moshiri E, Modir H, Navabi M, Naziri M. Comparison Effect of Ketamin-Propofol versus Alfentanil-Propofol for Creating Analgesia and Sedation during Cystoscopy. J Arak Uni Med Sci. 2014; 17 (1)
URL: http://jams.arakmu.ac.ir/article-1-2747-en.html
1- Asistant Professor, Department of Anesthesiology, Arak University of Medical sciences, Arak, Iran
2- Department of Anesthesiology, Vali-Asr Hospital, Arak University of Medical sciences, Arak, Iran , he_modir@yahoo.com
3- Anesthesiology Expert, Arak University of Medical sciences, Arak, Iran
4- MSc in Statistics, Arak University of Medical sciences, Arak, Iran
Abstract:   (4915 Views)

Background: Pain is a complex medical problem creating which inadequate control pain results adverse effects on the patients physiological, metabolic and mental conditions.The aim of this study was comparison effect of Ketamin-propofol with Alfentanil-propofol on creating analgesia and sedation during cystoscopy and comparing the side effects of two drugs and patient and physician satissfaction.

Materials and Methods: In this double- blind clinical trial 140 person who were candidate for cystoscopy were randomly divided into two groups The first group received 1mcg/kg alfentanil with 1mg/kg propofol and the second group received 0.5 mg/kg ketamin with 1mg/kg propofol. Sedation score ,pain score, time of cystoscopy and hemodynamic changes determined and data were analyzed by SPSS.

Results: The mean of sedation in alfetanil group was significantly more than ketamin group(p=0.001) . The mean of pain score in alfetanil group was significantly less than ketamin group( p=0.001) .The time of cystoscopy in cystoscopy in alfetanil group was significantly less than ketamin group (p=0.001).

Conclusion: Results showed that alfentanil-propofol compare to ketamin-propofol reduced pain score and increased time of sedation with less side effects during cystoscopy .So this study supports the preference alfentanil compare to ketamin.

Full-Text [PDF 302 kb]   (1117 Downloads)    
Type of Study: Original Atricle | Subject: Anesthesia
Received: 2014/01/7 | Accepted: 2014/02/26

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