Volume 25, Issue 2 (June & July 2022)
J Arak Uni Med Sci 2022, 25(2): 214-229 |
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Soleimani A, Fathi M. Effect of Four Weeks of Ginger Supplementation Followed by Acute Eccentric and Concentric Training on Irisin and Insulin Levels, Insulin Resistance Index, and Lipid Profile of Young Women With Obesity: A Randomized Clinical trial. J Arak Uni Med Sci 2022; 25 (2) :214-229
URL: http://jams.arakmu.ac.ir/article-1-7205-en.html
URL: http://jams.arakmu.ac.ir/article-1-7205-en.html
1- Department of Exercise Physiology, Faculty of Literature and Humanities, Lorestan University, khoramabad, Iran.
2- Department of Exercise Physiology, Faculty of Literature and Humanities, Lorestan University, khoramabad, Iran. ,fathi.m@lu.ac.ir
2- Department of Exercise Physiology, Faculty of Literature and Humanities, Lorestan University, khoramabad, Iran. ,
Abstract: (1032 Views)
Background and Aim Recently, a myokine called irisin has been discovered that affects glucose level, obesity, metabolism and glucose homeostasis by browning of white adipose tissue and heat production. This study aims to evaluate the effect of four weeks of ginger supplementation followed by acute eccentric and concentric training on irisin and insulin levels, insulin resistance index, and lipid profile of young women with obesity.
Methods & Materials This is a randomized clinical trial. Participants were 50 young women (BMI >30 kg/m2, age: 24.86±2.87 years, height: 159.66±4.20 cm, and weight: 87.42±4.61 kg). After measuring their maximum oxygen consumption, they were randomly divided into five groups, two groups of supplementation, two groups of placebo, and one control group. The training protocol consisted of two sessions of acute eccentric and concentric activity. The supplementation groups consumed 2 g of ginger powder daily for 4 weeks. Blood samples were collected before and immediately after each activity. Data were analyzed using dependent t-test and one-way analysis of variance (ANOVA).
Ethical Considerations This study was registered by Iranian Registry of Clinical Trials (Code: IRCT201104246178N1) and was approved by the ethics committee of Ilam University of Medical Sciences (Code: IR.MEDILAM.REC.1395.192).
Results The irisin and insulin levels between increased and the glucose level decreased significantly in the supplementation groups (P<0.05). The change in insulin resistance index was not significantly different among the study groups (P>0.05). Based on the results of one-way ANOVA, triglyceride and low-density lipoprotein levels decreased significantly (P<0.05), but the high-density lipoprotein level showed no significant difference (P<0.05). The total cholesterol level was not significantly different in terms of exercise type (P> 0.05) but was significantly different in terms of supplementation type (P<0.05).
Conclusion Long-term consumption of ginger along with regular exercise can be an effective method for lowering glucose level and causing favorable changes in irisin level, insulin resistance, and lipid profile in young women with obesity.
Methods & Materials This is a randomized clinical trial. Participants were 50 young women (BMI >30 kg/m2, age: 24.86±2.87 years, height: 159.66±4.20 cm, and weight: 87.42±4.61 kg). After measuring their maximum oxygen consumption, they were randomly divided into five groups, two groups of supplementation, two groups of placebo, and one control group. The training protocol consisted of two sessions of acute eccentric and concentric activity. The supplementation groups consumed 2 g of ginger powder daily for 4 weeks. Blood samples were collected before and immediately after each activity. Data were analyzed using dependent t-test and one-way analysis of variance (ANOVA).
Ethical Considerations This study was registered by Iranian Registry of Clinical Trials (Code: IRCT201104246178N1) and was approved by the ethics committee of Ilam University of Medical Sciences (Code: IR.MEDILAM.REC.1395.192).
Results The irisin and insulin levels between increased and the glucose level decreased significantly in the supplementation groups (P<0.05). The change in insulin resistance index was not significantly different among the study groups (P>0.05). Based on the results of one-way ANOVA, triglyceride and low-density lipoprotein levels decreased significantly (P<0.05), but the high-density lipoprotein level showed no significant difference (P<0.05). The total cholesterol level was not significantly different in terms of exercise type (P> 0.05) but was significantly different in terms of supplementation type (P<0.05).
Conclusion Long-term consumption of ginger along with regular exercise can be an effective method for lowering glucose level and causing favorable changes in irisin level, insulin resistance, and lipid profile in young women with obesity.
Type of Study: Original Atricle |
Subject:
Basic Sciences
Received: 2022/06/8 | Accepted: 2022/05/31
Received: 2022/06/8 | Accepted: 2022/05/31
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