Volume 25, Issue 2 (June & July 2022)
J Arak Uni Med Sci 2022, 25(2): 174-187 |
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Mohammadi F, Nikrou M, Sadeghi K, Askarifard F, Sayyadi M. The Role of Hemostatic System and the Importance of Blood Coagulation in COVID-19: A Review Study. J Arak Uni Med Sci 2022; 25 (2) :174-187
URL: http://jams.arakmu.ac.ir/article-1-7285-en.html
URL: http://jams.arakmu.ac.ir/article-1-7285-en.html
1- Student Research Committee, Arak University of Medical Sciences, Arak, Iran.
2- Department of Laboratory Sciences, Faculty of Paramedicine, Arak University of Medical Sciences, Arak, Iran. ,m.sayadi@arakmu.ac.ir
2- Department of Laboratory Sciences, Faculty of Paramedicine, Arak University of Medical Sciences, Arak, Iran. ,
Abstract: (1031 Views)
Background and Aim Coronavirus disease 2019 (COVID-19) is a respiratory disorder that can affect many body systems, including the hemostatic system. In this study, we aim to investigate the role of hemostatic system and the blood coagulation in COVID-19.
Methods & Materials In this review study, the articles were searched using the keywords COVID-19, Respiratory infection, and Coagulopathy in Google Scholar, PubMed, Google Springer and Science Direct databases.
Ethical Considerations Ethical principles in writing this article were observed in accordance with the guidelines of the National Ethics Committee and the Committee on Publication Ethics (COPE).
Results Many changes in the coagulation profile of infected patients were reported, including changes in the platelet count, fibrinogen/fibrin degradation product, D-Dimer, fibrinogen, prothrombin time, and activated partial thromboplastin time. With the increase in the number of patients with COVID-19, several studies found out the occurrence of thrombosis and coagulopathy in patients.
Conclusion Due to the increase in the occurrence of coagulation disorders in patients with COVID-19, the administration of anticoagulants is needed for their treatment; it can play an effective role in improving the prognosis of patients.
Methods & Materials In this review study, the articles were searched using the keywords COVID-19, Respiratory infection, and Coagulopathy in Google Scholar, PubMed, Google Springer and Science Direct databases.
Ethical Considerations Ethical principles in writing this article were observed in accordance with the guidelines of the National Ethics Committee and the Committee on Publication Ethics (COPE).
Results Many changes in the coagulation profile of infected patients were reported, including changes in the platelet count, fibrinogen/fibrin degradation product, D-Dimer, fibrinogen, prothrombin time, and activated partial thromboplastin time. With the increase in the number of patients with COVID-19, several studies found out the occurrence of thrombosis and coagulopathy in patients.
Conclusion Due to the increase in the occurrence of coagulation disorders in patients with COVID-19, the administration of anticoagulants is needed for their treatment; it can play an effective role in improving the prognosis of patients.
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