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Bayani M, Shafiei Lialestani S, Almasi-Hashiani A, Mirhoseini S H. Investigating the effectiveness of different antimicrobials agents on the decrease of microbial biofilms of dental unit waterlines: A Systematic review. J Arak Uni Med Sci 2022; 25 (5) :20-30
URL: http://jams.arakmu.ac.ir/article-1-7328-en.html

Introduction: Dental unit water lines (DUWL) are a potential place for the accumulation of microorganisms and the formation of microbial biofilm, which exposes people to infection risk. This study aimed to investigation of the effectiveness of four commonly used substances and selection of most effective disinfectant in DUWLs disinfection.
Methods: This systematic review study was conducted based on PRISMA templates and the PubMed, Scopus and Web of Science databases with a specific search strategy were examined. In this systematic review study, the effectiveness of 4 disinfectants including: hydrogen peroxide, chlorhexidine, chlorine-dioxide, sodium hypochlorite on microbial biofilms in the DUWL was investigated. The study was conducted on July 10, 2021, and finally the data of all studies related to the subject of this systematic review were extracted. This study was approved by the Research Ethics Committee at Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1399.347).
Results: All four disinfectants in sufficient concentration and time can be useful and effective. If the biofilm in DUWL is old and stabilized, it will affect the effectiveness of these materials and it will take longer to remove.
Conclusions: The use of materials in combination can cover all the microbial spectrum present in the biofilm of this area, and even fixed biofilms can be removed with extended and continuous use.