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Volume 17, Issue 1 (4-2014)                   J Arak Uni Med Sci 2014, 17(1): 0-0 | Back to browse issues page

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Malekirad A A, Abdollahi M, Fazilati M, Igani N, Baghinia M R, Taheri A et al . The Protective Effect of Poly Antioxidant Silivit on Oxidative Stress and Blood Parameters in Workers Exposure to Organic Solvents. J Arak Uni Med Sci. 2014; 17 (1)
URL: http://jams.arakmu.ac.ir/article-1-2161-en.html
1- Department of Biology, Payam Noor University, Iran , ak_malekirad@yahoo.com
2- tehran university of medical science
3- payame noor university
4- Arak University of mrdical science
5- islamic azad university
Abstract:   (5763 Views)

Introduction: Paints are composed of extensive variety of hazardous substances, such as organic solvents and heavy metals. Occupational exposure to paint increases oxidative stress, hematological disorders, and DNA injury. This study was performed to explore the beneficial effects of Selvit on the paint workers by measuring total antioxidant capacity, lipid peroxidation, and blood parameters as main oxidative stress biomarkers.

Materials and Methods: This clinical trial study was conducted on 25 male workers who worked in the paint factory. Serum markers such as total antioxidant capacity (TAC), lipid peroxidation (LPO) and also hematological parameters were measured before and after using Selvit (14 days). SPSS software was used for data analyses and paired t-test and Pearson correlation analysis were applied.

Results: Results showed that after using the Selvit, an increase in TAC and a decrease in LPO were observed but they were not significant. Also, aspartate transaninase significantly decreased after using Selvit and high density lipoprotein significantly increased.

Conclusion: Selvit have beneficial effect on hematological parameters due to its antioxidant capacity.

Full-Text [PDF 417 kb]   (1540 Downloads)    
Type of Study: Original Atricle | Subject: General
Received: 2013/02/5 | Accepted: 2014/02/26

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