Volume 11, Issue 2 (6-2008)                   J Arak Uni Med Sci 2008, 11(2): 56-63 | Back to browse issues page

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cyrus A, Pazoki S, Goodarzi D, Yavari M, Babayee E, Piraste S. Evaluation of the effects of oral Ketamine as an adjuvant drug in treatment of renal colic . J Arak Uni Med Sci 2008; 11 (2) :56-63
URL: http://jams.arakmu.ac.ir/article-1-220-en.html
1- , cyrus2nd@yahoo.com
Abstract:   (22764 Views)
Introduction: Oral Ketamine is used as a low side effect analgesic in comparison with opioids, in different pain syndromes. This study is designed to evaluate the effect of oral Ketamine in renal colic treatment. Materials and Methods: In this clinical trial study 104 patients with renal colic, hospitalized in emergency department, were divided in to two groups by Random block design. Group B received Pethidine (1 mg/kg up to 100 mg) and placebo, and group A received Pethidine with the same dose and Ketamine (0.5 mg/kg). All patients were assessed for pain by using VAS chart, for nausea by a 0-3 scale and for the number of vomiting at baseline and 1, 2 and 3 hours after taking drug. The results were analyzed by t-test. Results: Average pain score and vomiting in all times and nausea score in one and three hours after receiving drugs were reduced significantly in patients who took Pethidine and Ketamine comparing patients who took Pethidine and placcbo(p < 0.05). Conclusion: Regarding the significant effect of Ketamine in reduction of pain, nausea and vomiting without side effects, it is possible to use Ketamine as an adjuvant drug in treatment of renal colic and to reduce narcotic dosage.
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Subject: General
Received: 2009/03/5

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