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Introduction: Studies have shown that there is a relationship between metabolic syndrome and coronary heart disease. Hypertension is a common risk factor of both cardiovascular diseases and metabolic syndrome. The aim of this study is to determine the prevalence of metabolic syndrome phenotypes in patients with hypertension in Isfahan and Markazi provinces in center areas of Iran. Materials and Methods: This cross-sectional study was implemented in Isfahan and Markazi provinces in year 2001. Sampling method was random-clustering. 12514 people from both sexes who were above 19 years old were considered which based on ATP III, 1936 person of them had metabolic syndrome. Based on the definition, these people were those who at least had three of the following factors abnormally: HTN, FBS, TG, HDL and WC. Also hypertension was considered for all groups. Data was analyzed using Chi square test and Odds ratio. Results: The prevalence of metabolic syndrome was 0.6% to 7.5% in central areas of Iran. The most prevalent of metabolic syndrome was in hypertensive women with high TG and WC and the least prevalent was in hypertensive men with these two phenotypes: 1-high FBS and WC, and 2-high FBS and low HDL (p<0.05). Overall prevalence of metabolic syndrome in hypertensive people in the most of urban population was more than rural population. Conclusion: Results showed that hypertension is associated with different metabolic syndromes, especially in women with central obesity and dyslipidemia which necessitates more attention in preventing and treatment of the disease in this high risk group.

Keywords: Hypertension, metabolic syndrome, cardiovascular disease, hyperlipidemia, diabetes

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