Background: Cardiac troponin T and creatine kinase are used as biological markers for cardiomyocytes and its levels in serum are used as indicators of myocardial cell injury. The purpose of this study was to compare the effects of 3 different training protocols (runing, swimming, and pedaling training) on myocardial cell injury biomarkers in young girls.

Materials and Methods: In this semi-experimental study with pretest–posttest design, ten healthy young girls (aged 23.0±1.6 y) were selected in a convenience sampling way. The subjects performed three types of exercise in 7 days interval. Blood sample was assessed before and after the exercise sessions. Data were analyzed using t-test and analysis of variance.

Results: Our results indicated that creatin kinase increased significantly after three types of exercise (p<0.05). Running exercise led to greater increase in serum creatine kinase (p<0.05). Also, troponin T levels significantly were increased after three types of exercise (p<0.05), although no significant differences were observed between exercise types (p>0.05).

Conclusion: Our data suggest that intensive exercise is associated with cardiac damage in less trained girls and the type of exercise is determinants of the magnitude of myocardial injury biomarkers release.