Volume 21, Issue 6 (12-2018)
J Arak Uni Med Sci 2018, 21(6): 99-106 |
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Mohaghegh F, Mohseni M, Robatmili N, Bayatiani M R, Seif F, Mostafavi N S. The Comparison of The Received Doses of Tumoral and Organs at Risk (Spine and Thyroid) between Mixed Photon-Electron Beam Method and Photon Therapy in Supraclavicular Region of Patients with Right Side Breast Cancer that Endure Mastectomy. J Arak Uni Med Sci 2018; 21 (6) :99-106
URL: http://jams.arakmu.ac.ir/article-1-5347-en.html
URL: http://jams.arakmu.ac.ir/article-1-5347-en.html
Fatholah Mohaghegh1 
, Mehran Mohseni 2, Nasrin Robatmili3 , Mohamad Reza Bayatiani4 , Fatemeh Seif4 , Nayyer Sadat Mostafavi5
, Mehran Mohseni 2, Nasrin Robatmili3 , Mohamad Reza Bayatiani4 , Fatemeh Seif4 , Nayyer Sadat Mostafavi5
1- Arak University of Medical Sciences, Arak, Iran.
2- Department of Radiology-Medical Physics, Kashan School of Paramedical Sciences, Kashan University of Medical Sciences, Kashan, Iran. , mehran.m1352@yahoo.com
3- Kashan School of Paramedical Sciences, Kashan University of Medical Sciences, Kashan, Iran.
4- Department of Radiotherapy, Arak University of Medical Sciences, Arak, Iran.
5- Esfahan School of Paramedical Sciences, Esfahan University of Medical Sciences, Esfahan, Iran.
2- Department of Radiology-Medical Physics, Kashan School of Paramedical Sciences, Kashan University of Medical Sciences, Kashan, Iran. , mehran.m1352@yahoo.com
3- Kashan School of Paramedical Sciences, Kashan University of Medical Sciences, Kashan, Iran.
4- Department of Radiotherapy, Arak University of Medical Sciences, Arak, Iran.
5- Esfahan School of Paramedical Sciences, Esfahan University of Medical Sciences, Esfahan, Iran.
Abstract: (2587 Views)
Background and Aim: Radiation therapy is the destruction of cancer cells that in all patients with breast cancer reduces tumor recurrence, relieves pain in local tumors and metastases. There are different treatment methods around the world such as electron, photon alone or a combination of both types of fields.
Materials and Methods: In this study, photon therapy (PT) and mixed photon-electron therapy (MPET) were used to treat malignancies of the supraclavicular lymph nodes. 30 patients with right-sided breast cancer with local lymph node metastasis were recruited. The ISOgray software was utilized to collect data about treatment planning methods with PT and MPET.
Findings: The maximum and mean delivered doses of radiation to the supraclavicular region were 52.08±1.64, 42.59±0.51 Gy and 54.24±1.64, 43.67±0.43 Gy in the PT and MPET methods, respectively. The mean irradiated volumes of supraclavicular fossa that received 90% of the radiation dose were 59.74±1.94% and 70.26±0.94% in the PT and MPET methods, respectively (p=0.004). The maximum doses delivered to the spine were 14.66±1.9 Gy and 10.22±0.92 Gy and the thyroid were 42.62±3.1 Gy and 37.67±5.02 Gy in the PT and MPET methods, respectively.
Conclusion: The maximum doses delivered to the spine and thyroid significantly diminished by the novel method. Additionally, supraclavicular region received higher maximum and mean doses in the new treatment modality compared to the conventional methods. The new method improved dose coverage for the tumor.
Materials and Methods: In this study, photon therapy (PT) and mixed photon-electron therapy (MPET) were used to treat malignancies of the supraclavicular lymph nodes. 30 patients with right-sided breast cancer with local lymph node metastasis were recruited. The ISOgray software was utilized to collect data about treatment planning methods with PT and MPET.
Findings: The maximum and mean delivered doses of radiation to the supraclavicular region were 52.08±1.64, 42.59±0.51 Gy and 54.24±1.64, 43.67±0.43 Gy in the PT and MPET methods, respectively. The mean irradiated volumes of supraclavicular fossa that received 90% of the radiation dose were 59.74±1.94% and 70.26±0.94% in the PT and MPET methods, respectively (p=0.004). The maximum doses delivered to the spine were 14.66±1.9 Gy and 10.22±0.92 Gy and the thyroid were 42.62±3.1 Gy and 37.67±5.02 Gy in the PT and MPET methods, respectively.
Conclusion: The maximum doses delivered to the spine and thyroid significantly diminished by the novel method. Additionally, supraclavicular region received higher maximum and mean doses in the new treatment modality compared to the conventional methods. The new method improved dose coverage for the tumor.
Type of Study: Original Atricle |
Subject:
Basic Sciences
Received: 2017/09/29 | Accepted: 2018/10/10
Received: 2017/09/29 | Accepted: 2018/10/10
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