Volume 22, Issue 2 (6-2019)
J Arak Uni Med Sci 2019, 22(2): 106-114 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Najafi R, Amiri F, Roshanaei G, Abbasi M. Assessment of One-, Three- and Five-Year Survival Rates in Patients with Colon Cancer in Hamedan Province from 2003 to 2017. J Arak Uni Med Sci 2019; 22 (2) :106-114
URL: http://jams.arakmu.ac.ir/article-1-5960-en.html
URL: http://jams.arakmu.ac.ir/article-1-5960-en.html
1- Student Research Center, Department of Biostatistics, Faculty of Health, Hamedan University of Medical Sciences, Hamedan, Iran.
2- Department of Health and Epidemiology, Arak University of Medical Sciences, Arak, Iran.
3- Student Research Center, Department of Biostatistics, Faculty of Health, Hamedan University of Medical Sciences, Hamedan, Iran. ,gh.roshanaei@umsha.ac.ir
4- Faculty of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran.
2- Department of Health and Epidemiology, Arak University of Medical Sciences, Arak, Iran.
3- Student Research Center, Department of Biostatistics, Faculty of Health, Hamedan University of Medical Sciences, Hamedan, Iran. ,
4- Faculty of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran.
Abstract: (3033 Views)
Background and Aim: Colon cancer is one of the most common cancers in the gastrointestinal tract. Colon cancer is the third death cause among cancers. The aim of this study was to estimate the survival rate and determine the effective factors in colon cancer patients.
Materials and Methods: In this study, 193 colon cancer patients referring to Hamadan Imam Khomeini Clinic during the years 2003-2017 in a retrospective cohort study were used. Follow up of all patients was done by referral and phone call up to 2017. The Kaplan -Meyer model was used to estimate the survival of patients. Also, the effect of prognostic factors on the survival of patients was obtained by Cox regression model. The software used to analyze the data was STATA 11 and the significance level was 0.05.
Ethical Considerations: This study with research ethics code IR.UMSHA.REC.1396.144 was approved in Research Ethics Committee of Hamadan University of medical sciences, Iran.
Findings: The mean age of the patients at diagnosis was 57.09 ± 12.9 years. The probability of survival of one-, three- and five-year was 0.82, 0.61 and 0.48 percent, respectively. Also, the cancer stage has a significant effect on survival time of the patients.
Conclusion: Based on the Cox model, only the stage of cancer was effective on the survival time of patients with colon cancer. Therefore, timely diagnosis also helps prevent disease progression, as well as increase the survival time of the patient, especially at an advanced age.
Materials and Methods: In this study, 193 colon cancer patients referring to Hamadan Imam Khomeini Clinic during the years 2003-2017 in a retrospective cohort study were used. Follow up of all patients was done by referral and phone call up to 2017. The Kaplan -Meyer model was used to estimate the survival of patients. Also, the effect of prognostic factors on the survival of patients was obtained by Cox regression model. The software used to analyze the data was STATA 11 and the significance level was 0.05.
Ethical Considerations: This study with research ethics code IR.UMSHA.REC.1396.144 was approved in Research Ethics Committee of Hamadan University of medical sciences, Iran.
Findings: The mean age of the patients at diagnosis was 57.09 ± 12.9 years. The probability of survival of one-, three- and five-year was 0.82, 0.61 and 0.48 percent, respectively. Also, the cancer stage has a significant effect on survival time of the patients.
Conclusion: Based on the Cox model, only the stage of cancer was effective on the survival time of patients with colon cancer. Therefore, timely diagnosis also helps prevent disease progression, as well as increase the survival time of the patient, especially at an advanced age.
References
1. Baghestani AR, Daneshvar T, Pourhoseingholi MA, Asadzade H. Survival of colorectal cancer patients in the presence of competing-risk. Asian Pac J Cancer Prev. 2014; 15(15):6253-5.
2. Moradi A, Khayamzadeh M, Guya MM, Mirzaei HR, Salmanian R, Rakhsha A, et al. Survival of colorectal cancer in Iran. Asian Pac J Cancer Prev. 2009; 10(4):583-6.
3. Esna-Ashari F, Sohrabi M, Abadi A, Mehrabian A, Mofid B, Bohluli M, et al. Colorectal cancer prevalence according to survival data in Iran-2007. Iranian Journal of Cancer Prevention. 2009; 2(1):15-8.
4. Asghari-Jafarabadi M, Hajizadeh E, Kazemnejad A, Fatemi SR. Recognition of the factors affecting survival in colon and rectal cancer patients referred to RCGLD center of Shahid Beheshti University of Medical Sciences: accelerated failure time parametric survival analysis with frailty. Journal of Shahrekord Uuniversity of Medical Sciences. 2010; 12.
5. Kesse E, Clavel-Chapelon F, Boutron-Ruault M-C. Dietary patterns and risk of colorectal tumors: a cohort of French women of the National Education System (E3N). American journal of epidemiology. 2006; 164(11):1085-93.
6. Wei EK, Giovannucci E, Wu K, Rosner B, Fuchs CS, Willett WC, et al. Comparison of risk factors for colon and rectal cancer. International journal of cancer. 2004; 108(3):433-42.
7. Van der Pool A, Damhuis R, Ijzermans J, de Wilt J, Eggermont A, Kranse R, et al. Trends in incidence, treatment and survival of patients with stage IV colorectal cancer: a population‐based series. Colorectal Disease. 2012; 14(1):56-61.
8. Vakili M, Aghakoochak A, Pirdehghan A, Shiryazdy M, Saffarmoghadam A. The Survival Rate of Patients with Colorectal Cancer in Yazd during 2001-2011. Journal of Shahid Sadoughi University of Medical Sciences. 2014; 22(3):1187-95.
9. AA KZ, Saadat A, Jalalian HR, Esmaeili M. Epidemiology and survival analysis of colorectal cancer and its related factors. Trauma Monthly. 2011; 2010(04, Winter): 239-43.
10. Aryaie M, Roshandel G, Semnani S, Asadi-Lari M, Aarabi M, Vakili MA, et al. Predictors of colorectal cancer survival in Golestan, Iran: a population-based study. Epidemiology and health. 2013; 35.
11. Majek O, Gondos A, Jansen L, Emrich K, Holleczek B, Katalinic A, et al. Sex differences in colorectal cancer survival: population-based analysis of 164,996 colorectal cancer patients in Germany. PLoS One. 2013; 8(7):e68077.
12. Asghari Jafarabadi M, Hajizadeh E, Kazemnejad A, Fatemi S. Comparison the role of BMI, pathologic stage and hereditary related factors on survival between colon and rectal cancers: frailty competing risks model. Iranian Journal of Epidemiology. 2010; 6(3):35-49.
13. Moghimi DB, Safaei A, Zali MR. Survival rates and prognostic factors in colorectal cancer patients. 2008.
14. Mehrkhani F, Nasiri S, Donboli K, Meysamie A, Hedayat A. Prognostic factors in survival of colorectal cancer patients after surgery. Colorectal disease. 2009; 11(2):157-61.
15. Ansari R, Amjadi H, Norozbeigi N, Zamani F, Mir-Nasseri S, Khaleghnejad A, et al. Survival analysis of colorectal cancer in patients underwent surgical operation in Shariati and Mehr Hospital-Tehran, in a retrospective study. Govaresh. 2007; 12(1):7-15.
16. Rafiemanesh H, Pakzad R, Abedi M, Kor Y, Moludi J, Towhidi F, et al. Colorectal cancer in Iran: Epidemiology and morphology trends. EXCLI Journal. 2016; 15:738-44.
17. Tabatabaie SA, Hashemi SM, Ahmadi A. Prognostic Factor and Survival of Patients with Colorectal Cancer after Resection of Pulmonary Metastases. Journal of Isfahan Medical School. 2011; 28(124).
18. Mehrabani D, Almasi-Hashiani A. Evaluation of the 5-year survival rate and demographic factors in colorectal cancer patients. ZUMS Journal. 2012; 20(82):12-9.
19. Nasiri S, Sorush A, Karamnezhad M, Mehrkhani F, Mosafa S, Hedayat A. Prognostic Factors in the Survival Rate of Colorectal Cancer Patients after Surgery. 2010.
20. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA: a cancer journal for clinicians. 2011; 61(2):69-90.
21. Vakili M, Aghakoochak A, Pirdehghan A, Shiryazdy M, Saffarmoghadam A. The Survival Rate of Patients with Colorectal Cancer in Yazd during 2001-2011. The Journal of Shahid Sadoughi University of Medical Sciences. 2014; 22(3):1187-95.
22. Birgisson H, Talbäck M, Gunnarsson U, Påhlman L, Glimelius B. Improved survival of cancer of the colon and rectum in Sweden. Colorectal Disease Supplement. 2003; 5:3.
23. vakili M, Chahmatki F, Ansari M, Rahimi S, Baeradeh N. Survival Rate of Patients with Colorectal Cancer in Charmahal and Bakhtiari Province, Iran, 2000- 2010. Armaghane danesh. 2016; 20(12):1086-95.
24. Fernandez E, Bosetti C, La CV, Levi F, Fioretti F, Negri E. Sex differences in colorectal cancer mortality in Europe, 1955-1996. European journal of cancer prevention: the official journal of the European Cancer Prevention Organisation (ECP). 2000; 9(2): 99-104.
25. Burgess L. Colorectal cancer: epidemiology and genetics. Colorectal Cancer London. 2005: 27.
26. Roshanaei G, Komijani A, Sadighi A, Faradmal J. Prediction of survival in patients with colorectal cancer referred to the Hamadan MRI center using of Weibull parameter model and determination of its risk factors during 2005-2013; 2014.
27. Labianca R, Beretta GD, Kildani B, Milesi L, Merlin F, Mosconi S, et al. Colon cancer. Critical reviews in oncology/hematology. 2010; 74(2):106-33.
28. Zampino MG, Labianca R, Beretta GD, Magni E, Gatta G, Leonardi MC, et al. Rectal cancer. Critical reviews in oncology/hematology. 2009; 70(2):160-82.
29. Wilkes G, Hartshorn K, editors. Colon, rectal, and anal cancers. Seminars in oncology nursing; 2009: Elsevier.
30. Shaikh AJ, Raza S, Shaikh AA, Idress R, Kumar S, Rasheed YA, et al. Demographics, pathologic patterns and long-term survival in operable colon cancers: local experience in Pakistan. Asian Pac J Cancer Prev. 2009; 10(3):361-4.
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
