Volume 23, Issue 4 (October & November 2020)
J Arak Uni Med Sci 2020, 23(4): 450-461 |
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Amani A, Kamali A, Sadeghi B, Sistani A R, Tavakolizadeh M, Ghodibigi S, et al . Comparison of the Effectiveness of Chelleh Daghi Herbal Ointment and Piroxicam Gel on Ankle Sprains. J Arak Uni Med Sci 2020; 23 (4) :450-461
URL: http://jams.arakmu.ac.ir/article-1-6246-en.html
URL: http://jams.arakmu.ac.ir/article-1-6246-en.html
Alireza Amani1 
, Ali Kamali2 , Bahman Sadeghi 3, Ali Reza Sistani4 , Mahdi Tavakolizadeh5 , Sajad Ghodibigi6 , Farid Saghabi7 , Mojtaba Ahmadlou8
, Ali Kamali2 , Bahman Sadeghi 3, Ali Reza Sistani4 , Mahdi Tavakolizadeh5 , Sajad Ghodibigi6 , Farid Saghabi7 , Mojtaba Ahmadlou8
1- Department of Orthopedics, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
2- Department of Anesthesiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
3- Department of Social Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran. ,dr.sadeghis@arakmu.ac.ir
4- Department of Emergency Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
5- Department of Pharmacognosy, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
6- Bioparticulate Company Tehran, Tehran, Iran.
7- Arak Health Center, Arak, Iran.
8- Clinical Development Research Center, Amiralmomenin Hospital, Arak University of Medical Science, Arak, Iran.
2- Department of Anesthesiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
3- Department of Social Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran. ,
4- Department of Emergency Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
5- Department of Pharmacognosy, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
6- Bioparticulate Company Tehran, Tehran, Iran.
7- Arak Health Center, Arak, Iran.
8- Clinical Development Research Center, Amiralmomenin Hospital, Arak University of Medical Science, Arak, Iran.
Abstract: (2514 Views)
Background and Aim: Ankle injuries are among the most common musculoskeletal injuries in sports, accounting for 10% to 15% of all injuries. Since controlling pain and inflammation in ankle sprains is one of the main goals of treatment, we decided to compare the therapeutic effects of Cheleh daghi Herbal ointment with a common therapeutic gel such as piroxicam.
Methods & Materials: This study was performed as a double-blinded clinical trial for 6 months from January 2019 to August 2019. After referral, all patients completed the consent form, and the patient's details and study variables were recorded by the evaluator in the research form. To measure joint inflammation, we measured the ankle with a meter tape in the ankle area (cm) and recorded. A goniometer was also used to measure the degree of ankle movements. The symptoms of ankle ecchymosis were also checked by physical examination and observation and recorded in the checklist. Statistical analysis was performed in SPSS V. 18 using statistical tests (the Mann-Whitney U test, the Chi-square, and the independent t-test).
Ethical Considerations: The Research Ethics Committee of Arak University of Medical Sciences approved the study (Code: IR.ARAKMU.REC.1396.55) and registered by the Clinical Trial (Code: IRCT2017071720258N53).
Results: The Mean±SD age in the control group was 34.2±8.6 years, and in the case group was 35.4±8.9 years. There was no statistically significant difference according to the Mann-Whitney U test (P<0.05). Also, the Mean±SD height in the control group was 1.7±0.12 m and in the case group was 1.72±0.11 m. The results also showed a statistically significant difference between the two groups studied before and after the intervention regarding the mean indicators of pain, swelling, and inflammation around the joints (P<0.05).
Conclusion: The results of our study showed that Cheleh daghi Herbal ointment for 3 weeks could be more effective in reducing local pain and inflammation than piroxicam gel treatment.
Methods & Materials: This study was performed as a double-blinded clinical trial for 6 months from January 2019 to August 2019. After referral, all patients completed the consent form, and the patient's details and study variables were recorded by the evaluator in the research form. To measure joint inflammation, we measured the ankle with a meter tape in the ankle area (cm) and recorded. A goniometer was also used to measure the degree of ankle movements. The symptoms of ankle ecchymosis were also checked by physical examination and observation and recorded in the checklist. Statistical analysis was performed in SPSS V. 18 using statistical tests (the Mann-Whitney U test, the Chi-square, and the independent t-test).
Ethical Considerations: The Research Ethics Committee of Arak University of Medical Sciences approved the study (Code: IR.ARAKMU.REC.1396.55) and registered by the Clinical Trial (Code: IRCT2017071720258N53).
Results: The Mean±SD age in the control group was 34.2±8.6 years, and in the case group was 35.4±8.9 years. There was no statistically significant difference according to the Mann-Whitney U test (P<0.05). Also, the Mean±SD height in the control group was 1.7±0.12 m and in the case group was 1.72±0.11 m. The results also showed a statistically significant difference between the two groups studied before and after the intervention regarding the mean indicators of pain, swelling, and inflammation around the joints (P<0.05).
Conclusion: The results of our study showed that Cheleh daghi Herbal ointment for 3 weeks could be more effective in reducing local pain and inflammation than piroxicam gel treatment.
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