Volume 1, Issue 4 (Autumn 1997)
J Arak Uni Med Sci 1997, 1(4): 40-45 |
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Hashemieh M, Arzaniyan M T. A 10-Year Study of Hodgkins Disease in Mofid Childrens Hospital. J Arak Uni Med Sci 1997; 1 (4) :40-45
URL: http://jams.arakmu.ac.ir/article-1-6541-en.html
URL: http://jams.arakmu.ac.ir/article-1-6541-en.html
1- Arak University of Medical Sciences, Arak, Iran.
2- Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2- Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract: (1658 Views)
The pattern of Hodgkins disease was studied in 82 Iranian children in Mofid childrens Hospital over a 10- year period. There were 60 boys (73.2%) and 22 girls (2608%). The mean ages was 7years. According to Ann Arbor staging system, there have been 13 stagel (15.9% ) stagell ( 36.6%), 32 stagell (39%) and 7 stage IV patients (8.5%), 35 patients (42.7%) showed constitutional symptoms ( B group). The histologic subtypes among 82 children with Hodgkins disease has been mixed cellularity(45.1%), followed by nodular sclerosis (32.9%) and Lymphocyte predominant(18.3%). Lymphocyte depletion occurred only in three patients (3.7%). Most patients complaint about indolent peripheral lymphadenopathy as the initial sign of Hodgkins disese. Primary tumor sites were in the followed frequency: cervical (91.5%) of all patients), axillary (26.8%), inguinal (9.7%) and supraclavicular (8.5%) lymphonoders. 15 patients had received radiotherapy, 32 chemotherapy and 31 combined modality treatment. The disease free survival for 66 patients under follow up was 80% with mean time of 35 months.
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