Volume 2, Issue 8 (Autumn 1999)
J Arak Uni Med Sci 1999, 2(8): 36-41 |
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Hashemieh M. The Study of Incidence of Hepatitis C Infection Among Hemophilic and Thalassemic Patients in Marakazi Province. J Arak Uni Med Sci 1999; 2 (8) :36-41
URL: http://jams.arakmu.ac.ir/article-1-6594-en.html
URL: http://jams.arakmu.ac.ir/article-1-6594-en.html
School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Abstract: (1316 Views)
In this research , 44 hemophilic and 70 thalassemic patients were considered to obtain prevalence of hepatitis C infection by Elisa and PCR methods. In this study , liver function tests ( AST, ALT and alkaline phosphatase) evaluated for all cases and determination of HCV RNA was performed for cases which Anti-HCV was positive. 36 of hemophilic (81.8%) and 3 of thalassemic patients (4/3%) were Anti - HCv positive by Elisa Method and the same proportion was reported about HCV RNA. In thalassemic patients there was no significant relation between age ans sex with HCv infection, but relation between HCV and liver entzymes (ALT, AST and alkaline phosphatase) were significant. In hemophilic patients there was a significant relation between age and HCV infection but there was no meaningful relation between the yype and severity of hemophilia and HCV infection. Also the relation between HCV infection and liver enzymes (AST, ALT and alkaline phosphatase ) in these patients were significant.
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