Volume 13, Issue 4 (1-2011)                   J Arak Uni Med Sci 2011, 13(4): 106-114 | Back to browse issues page

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malekirad A A, fani A, abdollahi M, oryan S, babapor V, shariat zadeh S M A et al . Blood-urine and cognitive-mental parameters in mine workers exposed to lead and zinc. J Arak Uni Med Sci 2011; 13 (4) :106-114
URL: http://jams.arakmu.ac.ir/article-1-678-en.html
1- , ak_malekirad@yahoo.com
2- Teacher Training University of Tehran.
Abstract:   (16575 Views)
Background: Lead (Pb) brings about a variety of cognitive, mental, renal, and blood system disorders by inducing oxidative stress. The aim of this study is to compare blood and urine parameters in the workers exposed to Pb and zinc (Zn) with those in the control group. Materials and Methods: An analytical cross-sectional study was conducted with a total number of 134 subjects. The case group included 67 male workers with the age range of 22-65 who had at least worked a minimum of one work shift for two years in the Zn-Pb mine located in the southwest of Arak, Iran. Control subjects consisted of 67 farmers of a village near the mine who had no history of occupational exposure to Pb, Zn, and other metals. Mental disorders were evaluated through the standard Scl-90-R while cognitive disorders were evaluated via the Mini Mental Status Examination (MMSE). Results: The mean level of blood and urine parameters did not reveal significant differences between the two groups. The mean scores of physical complaints, anxiety, and aggression scales were significantly higher in the case group than the control (p<0.05), whereas the mean scores on MMSE did not reveal a significant difference between the two groups. Conclusion: The oxidative stress of Pb led to mental disorders as a result, the mine workers suffered from more psycho- pathology and are in need of greater care. Due to the impacts of Pb and Zn, the proper use of safety equipments and taking daily showers can reduce the risk of absorption of toxic agents and their subsequent hazards for workers.
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Subject: General
Received: 2010/04/6

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