Volume 7, Issue 1 (Spring 2004)
J Arak Uni Med Sci 2004, 7(1): 54-60 |
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Yazdi B, Nourzadeh M R. Comparison of the Therapeutic Effect and Side Effects of Sodium Propofol and Thiopental in Patients Treated With Electroconvulsive Therapy. J Arak Uni Med Sci 2004; 7 (1) :54-60
URL: http://jams.arakmu.ac.ir/article-1-6781-en.html
URL: http://jams.arakmu.ac.ir/article-1-6781-en.html
Abstract: (1624 Views)
Introduction: Electric seizure therapy is one of the most important treatments in psychiatry that is used as the least effective treatment for mental disorders. Significant anesthetics commonly used in Iran for this purpose are sodium thiopental with a dose of 0.5-3.5 mg/kg and propofol with a dose of 2-3 mg/kg, each of which has the above effects. It focuses on different systems of the body and causes different autonomic responses in patients. Therefore, it is necessary to compare the therapeutic effects and side effects of these two drugs in patients undergoing treatment for seizures with electricity.
method: In this study, which is a cross-sectional clinical trial study, 40 patients in the field of electronics seizure therapy were examined twice, one time with propofol and the next with sodium thiopental to induce anesthesia. Pre-, post-operative, and postoperative information were collected and analyzed by a questionnaire for seizure duration, blood pressure, heart rate, and level of awareness.
Results: The duration of seizures in propofol was less than in thiopental, which was statistically significant (P<0.001). Blood fluid in the case of thiopental increased significantly compared to propofol (P<0.001). The thiopental receptor group also showed a higher increase in heart rate, but this difference was not significant.
Conclusion: The use of propofol in seismic therapy with electricity has fewer side effects than thiopental and its use is recommended.
method: In this study, which is a cross-sectional clinical trial study, 40 patients in the field of electronics seizure therapy were examined twice, one time with propofol and the next with sodium thiopental to induce anesthesia. Pre-, post-operative, and postoperative information were collected and analyzed by a questionnaire for seizure duration, blood pressure, heart rate, and level of awareness.
Results: The duration of seizures in propofol was less than in thiopental, which was statistically significant (P<0.001). Blood fluid in the case of thiopental increased significantly compared to propofol (P<0.001). The thiopental receptor group also showed a higher increase in heart rate, but this difference was not significant.
Conclusion: The use of propofol in seismic therapy with electricity has fewer side effects than thiopental and its use is recommended.
Type of Study: Original Atricle |
Subject:
Basic Sciences
Received: 2021/01/27 | Accepted: 2004/03/29
Received: 2021/01/27 | Accepted: 2004/03/29
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