Volume 25, Issue 2 (June & July 2022)
J Arak Uni Med Sci 2022, 25(2): 188-199 |
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Abbasian S, Ravasi A A, Soori R, Choobineh S. Effect of 8 Weeks of High-intensity Interval Training on Adropin and Nitric Oxide Metabolites in Overweight Men. J Arak Uni Med Sci 2022; 25 (2) :188-199
URL: http://jams.arakmu.ac.ir/article-1-7075-en.html
URL: http://jams.arakmu.ac.ir/article-1-7075-en.html
1- Department of Sport Sciences, Khavaran Institute of Higher Education, Mashhad, Iran. , Sadeghabasian@gmail.com
2- Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
2- Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Abstract: (1792 Views)
Background and Aim Adropin is a new hormone plays an important role in improving lipid metabolism and vascular protection. The current study aims to determine the effect of eight weeks of high-intensity interval training (HIIT) on Adropin level and nitric oxide (NO) metabolites in overweight men.
Methods & Materials This is a quasi-experimental study with a pre-test/post-test design. Participants were 32 overweight men (Mean±SD age: 30.5±3.07 years, BMI: 27.93±4.2 kg/m2). They were randomly divided into two groups of HIIT (n=16) and control (n=16). The VO2max test was first conducted. Then, the HIIT group performed 8 weeks of HIIT (3 days per week) at 20 sessions of 30 seconds with a 13-s interval between each session. Body composition was measured using a bioelectrical impedance analyzer and the blood sampling was done for measuring Adropin and NO metabolites by ELISA kits in pre-test and post-test phases. The data analysis was done by repeated-measures ANOVA. The significance level was set at P<0.05.
Ethical Considerations This study was approved by the ethics committee of the University of Tehran (Code: IR.UT.REC.1395007). All procedures were in accordance with guidelines of the declaration of Helsinki.
Results There was a significant difference in Adropin between HIIT and control groups (0.88±0.256; 95% CI: 0.26-1.5 ng/mL). There was also a significant difference in NO metabolites between the two groups (7.5±3.03; 95% CI: 0.85-14.15 ng/ml). Moreover, there was a positive relationship between Adropin and NO metabolites in overweight men (r=0.498, P=0.0001).
Conclusion It seems that HIIT can attenuate cardiovascular diseases by increasing Adropin and NO and can improve cardiovascular fitness (VO2max) and body composition of men with overweight.
Methods & Materials This is a quasi-experimental study with a pre-test/post-test design. Participants were 32 overweight men (Mean±SD age: 30.5±3.07 years, BMI: 27.93±4.2 kg/m2). They were randomly divided into two groups of HIIT (n=16) and control (n=16). The VO2max test was first conducted. Then, the HIIT group performed 8 weeks of HIIT (3 days per week) at 20 sessions of 30 seconds with a 13-s interval between each session. Body composition was measured using a bioelectrical impedance analyzer and the blood sampling was done for measuring Adropin and NO metabolites by ELISA kits in pre-test and post-test phases. The data analysis was done by repeated-measures ANOVA. The significance level was set at P<0.05.
Ethical Considerations This study was approved by the ethics committee of the University of Tehran (Code: IR.UT.REC.1395007). All procedures were in accordance with guidelines of the declaration of Helsinki.
Results There was a significant difference in Adropin between HIIT and control groups (0.88±0.256; 95% CI: 0.26-1.5 ng/mL). There was also a significant difference in NO metabolites between the two groups (7.5±3.03; 95% CI: 0.85-14.15 ng/ml). Moreover, there was a positive relationship between Adropin and NO metabolites in overweight men (r=0.498, P=0.0001).
Conclusion It seems that HIIT can attenuate cardiovascular diseases by increasing Adropin and NO and can improve cardiovascular fitness (VO2max) and body composition of men with overweight.
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