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Volume 16, Issue 3 (6-2013)                   J Arak Uni Med Sci 2013, 16(3): 0-0 | Back to browse issues page

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Heidari Bateni M, Alizade S, Hashemi Tayer A, Almasi Hashyani A. The Effect of Autologus Platelet Glue on Healing Burn Wounds: An In Vivo Study. J Arak Uni Med Sci. 2013; 16 (3)
URL: http://jams.arakmu.ac.ir/article-1-2127-en.html
1- Department of Surgery, Arak University of Medical Sciences, Arak, Iran
2- Department of Hematology, Arak University of Medical Sciences, Arak, Iran , hashemi@Arakmu.ac.ir
3- Department of Epidemiology, Arak University of Medical Sciences, Arak, Iran
Abstract:   (7851 Views)

Background: Platelet glue is a human plasma product that is rich in platelets growth factors and fibrinogen and has haemostatic and healing properties. In the present study, the effect of fibrin sealant rich in platelet growth factors on healing burn wounds was evaluated.

Materials and Methods: This randomized clinical trial was done on 50 burn patients divided into two equal groups and followed for one month. Both groups received antibiotics during the treatment. Granulation tissue formation and epithelialization were the tokens of wound recovery and positive response to treatment. Data analysis was done by Fisher’s exact test, Mann-Whitney test, and t-test using SPSS software version 16.

Results: The mean of time to complete healing was significantly different in intervention and control groups (p=0.001). Time to recover 100% was 11.5±2.2 days in the intervention group and 16.2±5.3 days in the control group. The intervention group healed about 1.4 times faster than the control group.

Conclusion: Autologous platelet gel can be used as a new therapeutic approach in healing burn wounds. With this product, burn wounds can be expected to heal more quickly.

Full-Text [PDF 264 kb]   (2455 Downloads)    
Type of Study: Original Atricle | Subject: Oncology
Received: 2013/01/8 | Accepted: 2013/08/28

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