Background: The aim of this study was to test  the proposed model  for the impact of self-efficacy beliefs on parent’s anxiety and marital adjustment with mediating role of cognitive emotion regulation strategies among parents of chronically ill children of ahwaz city.

Materials and Methods: The statistical universe was all the parents of chronically ill children who was selected by Convenience sampling method.The research tools are included the self-efficacy questionnaire (SES), anxiety questionnaire (STAI), Spanier marital adjustment questionnaire  and Garnesfki cognitive emotion regulation strategies questionnaire.Amos 18 program software was applied for structural equation modeling (SEM).The indirect relationship was tested with bootstrap Amos 18 program software.

Results: The results revealed that the tested model had good fit indices.

Conclusion: Results revealed that self-efficacy beliefs directly influenced on parent's anxiety, marital adjustment, and adaptive and nonadaptive cognitive emotion regulation strategies. Also, adaptive cognitive emotion regulation strategies have a direct relation with parent's anxiety and marital adjustment. In addition, there was a direct relation between nonadaptive cognitive emotion regulation strategies and marital adjustment. Alternatively, self-efficacy beliefs directly influenced on anxiety and marital adjustment with mediating role of adaptive cognitive emotion tegulation strategies and indirectly influenced on adjustment with mediating role of nonadaptive cognitive emotion regulation strategies.