Volume 19, Issue 12 (3-2017)                   J Arak Uni Med Sci 2017, 19(12): 1-11 | Back to browse issues page

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Ebrahimi Monfared M, Sadegh M, Gohari Z. Effect of Melatonin and Vitamin E on EEG, Sleep Quality and Quality of Life of Shift-Working Nurses in Arak Hospitals. J Arak Uni Med Sci 2017; 19 (12) :1-11
URL: http://jams.arakmu.ac.ir/article-1-4602-en.html
1- Department of Neurology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
2- Department of Physiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
3- Department of Physiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran , m.sadegh@arakmu.ac.ir
Abstract:   (10079 Views)


Background: Melatonin regulates the sleep-wake cycle and is protected against oxidants. Vitamin E has antioxidant effect. The aim of this study was to investigate effect of melatonin and/or vitamin E on the EEG, sleep quality and quality of life of female nurses working in hospitals in Arak.

Materials and Methods: 60 female nurses were randomly selected from hospitals in the Arak city. Participants divided into three groups (melatonin3 mg/day, vitamin E 200 IU/day and melatonin and vitamin E groups) and a control group. Before and two months after the baseline, PSQTI and the quality of life of 26 questions questionnaire were completed and EEG was recorded. Finally, the findings for both groups before and after the intervention were compared with each other.

Results: The average of sleep quality showed an improvement in groups receiving melatonin and melatonin+vitamin E (p>0.05). While data of life quality did not show any significant change between groups. In EEG activity, α waves in the range of 8-10 Hz showed maximum increase in melatonin group and minimum increase in vitamin E group. Also, α wave in the range of 10-12 Hz revealed the most decrease in the melatonin group.

Conclusion: It seems simultaneous administration of melatonin and vitamin E is able to improve sleep quality. In addition, melatonin could improve alpha-waves of brain activity.

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Type of Study: Original Atricle | Subject: Nursing
Received: 2016/08/16 | Accepted: 2017/01/21

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