Volume 21, Issue 5 (10-2018)                   J Arak Uni Med Sci 2018, 21(5): 69-76 | Back to browse issues page

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Dalvandi M, Farahani H, Safari Rad R. Association of Lumber Disk Herniation with Serum Zinc Level. J Arak Uni Med Sci 2018; 21 (5) :69-76
URL: http://jams.arakmu.ac.ir/article-1-5740-en.html
1- Department of Neurosurgery. Faculty of Medicine, Arak University of Medical Science, Arak, IR, Iran.
2- Department of Biochemistry, Faculty of Medicine, Arak University of Medical Science, Arak, IR, Iran. , farahaniheidar@yahoo.com
3- Arak Medical Science University, I.R. Iran
Abstract:   (2728 Views)
Background and Aim: Low Back Pain is one of the most common complains of Human societies. LDH (Lumber Disk Herniation) is one of the relatively common causes of Low Back Pain. This study aimed to assay serum zinc cofactor in patients compared to healthy group.
Materials and Methods: Sixty patients which were diagnosed as a "known case of LDH" by the specialist and based on tests were chosen by simple selection method (30 men and 30 women). Also, 57 people were chosen as a control group (29 men and 28 women). measurement was done based on single reagent direct calorimetric method using the kit made by "Ziestchem diagnostics company, Iran".
Findings: Total, 117 objects were observed in case and control groups. Serum zinc level was measured in all of them. Obtained results were analyzed by Student t-test, and ꭕ2, by using SPSS software with the confidence interval of 95 percent. Results showed that 21.7% of patients with LDH were having high physical activity and 36.7% having low physical activity.
Conclusion: There was a significant difference between the mean serum zinc levels in patients with LDH compared to control group. Decrement in serum zinc may be considered as an distruption factor in the activity of enzymes involved in proteins biosynthesis.
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Type of Study: Original Atricle | Subject: Basic Sciences
Received: 2018/04/24 | Accepted: 2018/08/4

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