Volume 1, Issue 2 (Spring 1997)
J Arak Uni Med Sci 1997, 1(2): 27-33 |
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Pedram M. Kidney and Pregnancy. J Arak Uni Med Sci 1997; 1 (2) :27-33
URL: http://jams.arakmu.ac.ir/article-1-6518-en.html
URL: http://jams.arakmu.ac.ir/article-1-6518-en.html
Arak University of Medical Sciences, Arak, Iran.
Abstract: (1722 Views)
The retention of 500-900 meq sodium and 6-8 litre water, which is b diffused between extracellular fluid space of mother and fetues is performed in pregnancy slowly. When plasma volume increase by 30-50%, mean blood pressure decreases by 15% approximately. In the second half of the pregnancy, blood pressure increases slowly and it returns to its previous status, in the period of term. GFR is increases by 30-50% in the twelfth week of pregnancy, and it remains steady until the term period .Glucosuria and Aminoaciduria may be observed during the pregnancy. In this time ureters are dilated and it continues until the twelve weeks after delivery. The cardiac output goes up in the primary trimester and then it remains fixed until the term. Hypertension is still one of the main reason of morality both in mother and infetus. The best division of blood pressure in the pregnancy has advocated by American college of Gynecologist, which has got 4 parts:
A: hypertension which exactly relates to pregnancy ( Eclampsy , Pre-eclampsy)
B:chronic Hypertension with other causes
C:Chronic Hypertension which has been added by pre _Eclampsy
D: Pregnancy induced Hypertension
The other crucial problems in pregnancy is acute renal failure , which may be causes by renal isschmia by the effect of nephrotoxic agent. The cellular lesion might be revercible. It might be accomparied with complete renal function and might be irreversible, therefore it may lead to renal cortical necrosis. In addition to usual reasons of acute failure , some of them relates specifically to pregnancy. Only infectious, criminal abortions and malignant vomiting are reasons of failure in the beginning of pregnancy, which severe pre-eclampsy, placenta and placenta abruption are the main reasons of renal failure in the final phase of pregnancy.
A: hypertension which exactly relates to pregnancy ( Eclampsy , Pre-eclampsy)
B:chronic Hypertension with other causes
C:Chronic Hypertension which has been added by pre _Eclampsy
D: Pregnancy induced Hypertension
The other crucial problems in pregnancy is acute renal failure , which may be causes by renal isschmia by the effect of nephrotoxic agent. The cellular lesion might be revercible. It might be accomparied with complete renal function and might be irreversible, therefore it may lead to renal cortical necrosis. In addition to usual reasons of acute failure , some of them relates specifically to pregnancy. Only infectious, criminal abortions and malignant vomiting are reasons of failure in the beginning of pregnancy, which severe pre-eclampsy, placenta and placenta abruption are the main reasons of renal failure in the final phase of pregnancy.
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