Volume 7, Issue 3 (Autumn 2004)                   J Arak Uni Med Sci 2004, 7(3): 34-41 | Back to browse issues page

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Nakhai M R, Razavieh V, Mahdavi R, Palizvan M R, Madadi Noie S. Effect of Cis and Trans Fatty Acids Intake on Pentylen Tetrazol Kindling in Rats. J Arak Uni Med Sci 2004; 7 (3) :34-41
URL: http://jams.arakmu.ac.ir/article-1-6802-en.html
Abstract:   (737 Views)
Introduction: Impressive  research  demonstrates   the importance  of  essential  fatty  acids  for  many  physiological  and  bahavioral  mechanisms  in  both  human  and  animals.  Essential  fatty  acids  must  be  supplied  via  the  diet.  In  this  study  we  assessed  the  dietary  effects  of  cis  and  trans  fatty  acids  on  seizures  induced  by  pentylenetetrazol  in  rats.
Materials  and  Methods:  In this  study  animals  were  divided  into  four  groups.  In  the  test  groups  cis, trans  or  cis  and  trans  fatty  acids  were  add  to  the  standard  foods  of  rats  and  in  control  group  only  standard  food  was  dietary  administrated. After  one  month  kindling  was  established  in  rats  with  PTZ  in  subconvulsive  dose (45 mg/kg). convulsing  activities  were  monitored  for  20  min.
Results: Results  showed  that  there  was  no  meaningful  difference  between  rat  groups  receiving  cis, trantary  administration  of  cis  and  trans  fatty  acids  had  no  effect  on  penylenetetrazol  kindling  in  rats.s  or  cis  and  trans  fatty  acids  in  their  standard  food.
Conclusion: It  was  concluded  that  dietary  administration  of  cis  and  trans  fatty  acids  had  no  effect  on  pentylenetetrazol  kindling  in  rats. 
 
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Subject: General
Received: 2021/01/29 | Accepted: 2004/10/1

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